Clinical emergency care research in low-income and middle-income countries: opportunities and challenges

Aluisio, Adam R, Waheed, Shahan, Cameron, Peter, Hess, Jermey, Jacob, Shevin ORCID: https://orcid.org/0000-0003-2425-9394, Kissoon, Niranjan, Levine, Adam C, Mian, Asad, Ramlakhan, Shammi, Sawe, Hendry R and Razzak, Junaid (2019) 'Clinical emergency care research in low-income and middle-income countries: opportunities and challenges'. BMJ Global Health, Vol 4, Issue Suppl 6, e001289.

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Abstract

Disease processes that frequently require emergency care constitute approximately 50% of the total disease burden in low-income and middle-income countries (LMICs). Many LMICs continue to deal with emergencies caused by communicable disease states such as pneumonia, diarrhoea, malaria and meningitis, while also experiencing a marked increase in non-communicable diseases, such as cardiovascular diseases, diabetes mellitus and trauma. For many of these states, emergency care interventions have been developed through research in high-income countries (HICs) and advances in care have been achieved. However, in LMICs, clinical research, especially interventional trials, in emergency care are rare. Furthermore, there exists minimal research on the emergency management of diseases, which are rarely encountered in HICs but impact the majority of LMIC populations. This paper explores challenges in conducting clinical research in patients with emergency conditions in LMICs, identifies examples of successful clinical research and highlights the system, individual and study design characteristics that made such research possible in LMICs. Derived from the available literature, a focused list of high impact research considerations are put forth.

Item Type:	Article
Subjects:	W General Medicine. Health Professions > W 21 Medicine as a profession. WA Public Health > WA 30 Socioeconomic factors in public health (General) WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1136/bmjgh-2018-001289
Depositing User:	Stacy Murtagh
Date Deposited:	16 Sep 2019 10:49
Last Modified:	16 Sep 2019 10:49
URI:	https://archive.lstmed.ac.uk/id/eprint/12435

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