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Human bocavirus in Iranian children with acute respiratory infections

Naghipour, M., Cuevas, Luis ORCID:, Bakhshinejad, T., Dove, W. and Hart, C. Anthony (2007) 'Human bocavirus in Iranian children with acute respiratory infections'. Journal of Medical Virology, Vol 79, Issue 5, pp. 539-543.

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Human bocavirus (HBoV), a virus discovered in Sweden in 2005, has been associated with acute respiratory infections in young children and subsequent reports suggest that HBoV may have a worldwide distribution. This report describes the frequency and clinical presentation of HBoV in 261 Iranian children < 5 years old with acute respiratory infections attending two regional hospitals in Rasht, Iran in the winter of 2003-2004. Polymerase chain reaction (PCR) and reverse transcription PCR (RT-PCR) were used for the detection of HBoV and other respiratory pathogens from nasopharyngeal specimens. HBoV was detected in 21 (8%) children. Fifteen (12%) of these children were identified among 122 children admitted to hospital and 6 (4%) from 139 outpatients (P < 0.05). Most children with HBoV were less than 2 years (17/21, 81%) and 7 (33%) were less than 1 year old. Although HBoV was identified in all ages it affected slightly older children than the respiratory syncytial virus (RSV). The frequency of the virus varied from 1 (3%) in 40 patients in November to 7 (12%) of 61 in February, suggesting a seasonal pattern during the autumn and early winter. Seven children had co-infections with RSV, adenovirus or influenza A. The relatively high frequency of HBoV suggests that the virus may contribute substantially to acute respiratory infections in children.

Item Type: Article
Uncontrolled Keywords: human bocavirus acute respiratory infections children clinical presentation iran tract infections syncytial-virus human metapneumovirus association
Subjects: QW Microbiology and Immunology > Viruses > QW 160 Viruses (General). Virology
WC Communicable Diseases > Virus Diseases > Viral Respiratory Tract Infections. Respirovirus Infections > WC 505 Viral respiratory tract infections
WS Pediatrics > Diseases of Children and Adolescents > By System > WS 280 Respiratory system
Faculty: Department: Groups (2002 - 2012) > Child & Reproductive Health Group
Digital Object Identifer (DOI):
Depositing User: Ms Julia Martin
Date Deposited: 15 Nov 2010 11:13
Last Modified: 17 Jul 2020 10:58


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