Ecological zones rather than molecular forms predict genetic differentiation in the malaria vector Anopheles gambiae s.s. in Ghana

Yawson, A. E., Weetman, David ORCID: https://orcid.org/0000-0002-5820-1388, Wilson, M. D. and Donnelly, Martin ORCID: https://orcid.org/0000-0001-5218-1497 (2007) 'Ecological zones rather than molecular forms predict genetic differentiation in the malaria vector Anopheles gambiae s.s. in Ghana'. Genetics, Vol 175, Issue 2, pp. 751-761.

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Abstract

The malaria mosquito Anopheles gambiae s.s. is rapidly becoming a model for studies on the evolution of reproductive isolation. Debate has centered on the taxonomic status of two forms (denoted M and S) within the nominal taxon identified by point mutations in the X-linked rDNA region. Evidence is accumulating that there are significant barriers to gene flow between these forms, but that the barriers are not complete throughout the entire range of their distribution. We sampled Populations from across Ghana and Southern Burkina Faso, West Africa, front areas where the molecular forms occurred in both sympathy and allopatry. Neither Bayesian clustering methods nor F-ST-based analysis of microsatellite data found differentiation between the M and S molecular forms, but revealed strong differentiation among different ecological zones, irrespective of M/S status and with no detectable effect of geographical distance. Although no M/S hybrids were found in the samples, admixture analysis detected evidence of contemporary interform gene flow, arguably most pronounced in southern Ghana where forms Occur sympatrically. Thus, in the sampled area of West Africa, lack of differentiation between M and S forms likely reflects substantial introgression, and ecological barriers appear to be of greater importance in restricting gene flow.

Item Type:	Article
Uncontrolled Keywords:	population-structure west-africa DNA analysis reproductive isolation transferred sperm chromosomal forms complex sequence introgression polymorphism
Subjects:	QU Biochemistry > Genetics > QU 475 Genetic processes QX Parasitology > Insects. Other Parasites > QX 515 Anopheles
Faculty: Department:	Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI):	https://doi.org/10.1534/genetics.106.065888
Depositing User:	Ms Julia Martin
Date Deposited:	02 Nov 2010 09:55
Last Modified:	16 Sep 2019 09:16
URI:	https://archive.lstmed.ac.uk/id/eprint/1386

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