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Okomo, Uduak, Senghore, Madikay, Darboe, Saffiatou, Bojang, Ebrima, Akramuzzaman, SyedMohd, Hossain, Mohammad Jahangir, Nwakanma, Davis, Le Doare, Kirsty, Holt, Kathryn E, Hos, Nina Judith, Lawn, Joy E, Bentley, Stephen D and Kampmann, Beate (2020) 'Investigation of sequential outbreaks of Burkholderia cepacia and multidrug-resistant extended spectrum β-lactamase producing Klebsiella species in a West African tertiary hospital neonatal unit: a retrospective genomic analysis'. Lancet Microbe, Vol 1, Issue 3, E119-E129.
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Uduak_Outbreak_Bukholderia_Kebsiella_Lancet_Microbe_01Jul2020.pdf - Published Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (834kB) | Preview |
Abstract
Sick newborns admitted to neonatal units in low-resource settings are at an increased risk of developing hospital-acquired infections due to poor clinical care practices. Clusters of infection, due to the same species, with a consistent antibiotic resistance profile, and in the same ward over a short period of time might be indicative of an outbreak. We used whole-genome sequencing (WGS) to define the transmission pathways and characterise two distinct outbreaks of neonatal bacteraemia in a west African neonatal unit.
| Item Type: | Article |
|---|---|
| Subjects: | QW Microbiology and Immunology > Bacteria > QW 131 Gram-negative bacteria. QW Microbiology and Immunology > Bacteria > QW 138 Enterobacteriaceae WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WS Pediatrics > By Age Groups > WS 420 Newborn infants. Neonatology |
| Faculty: Department: | Education |
| Digital Object Identifer (DOI): | https://doi.org/10.1016/S2666-5247(20)30061-6 |
| Depositing User: | Paula Harding |
| Date Deposited: | 01 Oct 2020 16:56 |
| Last Modified: | 01 Oct 2020 16:56 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/15082 |
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