LSTM Home > LSTM Research > LSTM Online Archive

Prevalence of perinatal depression and its determinants in Mainland China: A systematic review and meta-analysis

Nisar, Anum, Yin, Juan, Waqas, Ahmed, Bai, Xue, Wang, Duolao ORCID:, Rahman, Atif and Li, Xiaomei (2020) 'Prevalence of perinatal depression and its determinants in Mainland China: A systematic review and meta-analysis'. Journal of Affective Disorders, Vol 277, pp. 1022-1037.

Prevalence of perinatal depression and its determinants in Mainland China - DWang.pdf - Accepted Version

Download (12MB) | Preview


Background: Perinatal depression is a maternal mental health condition that is associated with various adverse health outcomes both for the mothers and the babies. The study aim was to estimate the prevalence of perinatal depression and its risks and determinants in Mainland China.

Methods: Systematic searches were conducted in 10 major databases and random effect meta-analysis was performed to achieve the pooled variance of perinatal depression. Subgroup analyses were conducted based on region, scale, methods of diagnosis and study design. Meta-regression was performed with the variables such as age, quality assessment score and gross domestic product (GDP) of the province.

Results: Pooled prevalence of perinatal depression was 16.3% (CI=95%; 14.7% to 18.2%, P < 0.001), with antenatal depression 19.7% (CI=95%; 15.8% to 24.2%, P < 0.001) and postnatal depression 14.8% (CI=95%; 13.1% to 16.6%, P < 0.001). Significant publication bias was found and heterogeneity was I2= 98.13%. Lower socioeconomic status, poor physical health, anxiety about pregnancy and reduced social support were major risk factors while better living conditions and education were protective factors. The prevalence of perinatal depression showed a significant increasing trend in the last decade.

Limitations: The review does not include studies with small sample size (n <250). Moreover a narrative review of risk and protective factors was done, these were not included in meta-analysis.

Conclusion: The prevalence of perinatal depression in China is similar to low and middle-income countries. Urgent attention is needed to address this public health priority in China.

Item Type: Article
Subjects: WA Public Health > Statistics. Surveys > WA 950 Theory or methods of medical statistics. Epidemiologic methods
WM Psychiatry > WM 100 General works
WQ Obstetrics > WQ 500 Postnatal care
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):
Depositing User: Julie Franco
Date Deposited: 24 Aug 2020 13:36
Last Modified: 18 Jul 2021 01:02


View details

Actions (login required)

Edit Item Edit Item