LSTM Home > LSTM Research > LSTM Online Archive

Experimental Transmission of Plasmodium malariae to Anopheles gambiae

Pinilla, Yudi T, Boussougou-Sambe, Stravensky T, Gräßle, Sarah, Ngossanga, Barclaye, Doumba-Ndalembouly, Ange G, Weierich, Andrea, Bingoulou, Gedeon, Malinga, Emma G, Nguiffo-Nguete, Daniel, Ntoumi, Francine, Djogbénou, Luc, Issifou, Saadou, Wondji, Charles ORCID:, Adegnika, Ayola A and Borrmann, Steffen (2021) 'Experimental Transmission of Plasmodium malariae to Anopheles gambiae'. Journal of Infectious Disease, Vol 223, Issue 3, pp. 522-526.

[img] Text
Pinilla_et.al_2020_Manuscript_Transmission_P.malariae_clean.docx - Accepted Version

Download (77kB)


Our current knowledge of the clinical burden, biology, and
transmission of Plasmodium malariae is extremely scarce. To
start addressing some of those questions, we experimentally
infected Anopheles gambiae mosquitoes with fresh P. malariae
isolates obtained from asymptomatic individuals in Lambaréné,
Gabon. The proportion of mosquitoes infected via direct membrane
feeding assay with either P. malariae monoinfections
(16% [19 of 121]) or coinfections (28% [31 of 112]) was higher
after serum replacement than in parallel groups without serum
replacement (4% [4 of 102] and 4% [2 of 45], respectively;
P < .01). Our results show that isolates from asymptomatic
carriers can be used for experimental studies of P. malariae

Item Type: Article
Subjects: QX Parasitology > Protozoa > QX 135 Plasmodia
QX Parasitology > Insects. Other Parasites > QX 515 Anopheles
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
Faculty: Department: Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI):
Depositing User: Samantha Sheldrake
Date Deposited: 01 Sep 2020 13:52
Last Modified: 04 Jul 2021 01:02


View details

Actions (login required)

Edit Item Edit Item