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EP27-355-23 Characterization of the metabolic urine profile using nuclear magnetic resonance (NMR) spectroscopy to monitor treatment of tuberculosis

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Comella-del-Barrio,, P, Izquierdo-Garcia, JL, Muriel Moreno,, B, García-García, E, Millet, P, Molina-Pinargote, I, Prat-Aymerich, C, Ruiz-Cabello, J, Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 and Domínguez, J (2020) 'EP27-355-23 Characterization of the metabolic urine profile using nuclear magnetic resonance (NMR) spectroscopy to monitor treatment of tuberculosis' in The 51st Union World Conference on Lung Health, Online, 20 -24 October 2020.

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Abstract

The emergence of drug-resistant tuberculosis (TB) challenges the control of TB with an increase in treatment failure. Surveillance during treatment is essential to monitor adherence and treatment response.
Metabolomics can be used to obtain a "fingerprint" of the metabolites presents in a biological sample, allowing the study of sets of metabolites affected by host-pathogen interactions and the identification of therapeutic markers to improve the evaluation of the TB outcome.
In this proof of concept, we aimed to characterize the urinary metabolic profile of patients receiving anti-TB treatment and its association to TB treatment outcome.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	appears in VOLUME 24 NUMBER 10 OCTOBER 2020 SUPPLEMENT 2
Subjects:	WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General) WN Radiology. Diagnostic imaging > WN 100 General works. Stereoscopy. Electrokymography WN Radiology. Diagnostic imaging > WN 180 Diagnostic imaging (General) WN Radiology. Diagnostic imaging > Nuclear Medicine > WN 440 Nuclear medicine
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Depositing User:	Rachael O'Donoghue
Date Deposited:	11 Dec 2020 12:45
Last Modified:	11 Dec 2020 12:53
URI:	https://archive.lstmed.ac.uk/id/eprint/16294

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