An Evaluation of Programmatic Community-Based Chest X-ray Screening for Tuberculosis in Ho Chi Minh City, Vietnam.

Nguyen, Lan Huu, Codlin, Andrew J, Vo, Luan Nguyen Quang, Dao, Thang, Tran, Duc, Forse, Rachel J, Vu, Thanh Nguyen, Le, Giang Truong, Luu, Tuan, Do, Giang Chau, Truong, Vinh Van, Minh, Ha Dang Thi, Nguyen, Hung Huu, Creswell, Jacob, Caws, Maxine ORCID: https://orcid.org/0000-0002-9109-350X, Nguyen, Hoa Binh and Nguyen, Nhung Viet (2020) 'An Evaluation of Programmatic Community-Based Chest X-ray Screening for Tuberculosis in Ho Chi Minh City, Vietnam.'. Tropical medicine and infectious disease, Vol 5, Issue 4, p. 185.

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Abstract

Across Asia, a large proportion of people with tuberculosis (TB) do not report symptoms, have mild symptoms or only experience symptoms for a short duration. These individuals may not seek care at health facilities or may be missed by symptom screening, resulting in sustained TB transmission in the community. We evaluated the yields of TB from 114 days of community-based, mobile chest X-ray (CXR) screening. The yields at each step of the TB screening cascade were tabulated and we compared cohorts of participants who reported having a prolonged cough and those reporting no cough or one of short duration. We estimated the marginal yields of TB using different diagnostic algorithms and calculated the relative diagnostic costs and cost per case for each algorithm. A total of 34,529 participants were screened by CXR, detecting 256 people with Xpert-positive TB. Only 50% of those diagnosed with TB were detected among participants reporting a prolonged cough. The study's screening algorithm detected almost 4 times as much TB as the National TB Program's standard diagnostic algorithm. Community-based, mobile chest X-ray screening can be a high yielding strategy which is able to identify people with TB who would likely otherwise have been missed by existing health services.

Item Type:	Article
Subjects:	WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General) WF Respiratory System > Tuberculosis > WF 225 Mass chest X-ray
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.3390/tropicalmed5040185
Depositing User:	Julie Franco
Date Deposited:	20 Jan 2021 15:11
Last Modified:	20 Jan 2021 15:11
URI:	https://archive.lstmed.ac.uk/id/eprint/16709

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