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Modelling the impact of vector control on lymphatic filariasis programmes: current approaches and limitations

Davis, E L, Prada, J, Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981 and Hollingsworth, T D (2021) 'Modelling the impact of vector control on lymphatic filariasis programmes: current approaches and limitations'. Clinical Infectious Diseases. (In Press)

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Abstract

Vector control is widely considered an important tool for lymphatic filariasis (LF) elimination but is not usually included in programme budgets and has often been secondary to other policy questions in modelling studies. Evidence from the field demonstrates that vector control can have a large impact on programme outcomes and even halt transmission entirely, but implementation is expensive. Models of LF have the potential to inform where and when resources should be focused, but often simplify vector dynamics and focus on capturing human prevalence trends, making them comparatively ill-designed for direct analysis of vector control measures. We review the recent modelling literature and present additional results using a well-established model, highlighting areas of agreement between model predictions and field evidence, and discussing the possible determinants of existing disagreements. We conclude that there are likely to be long-term benefits of vector control, both on accelerating programmes and preventing resurgence.
Key words: lymphatic filariasis; vector control; modelling; elimination; resurgence.

Item Type: Article
Subjects: QX Parasitology > QX 4 General works
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
WH Hemic and Lymphatic Systems > Lymphatic System > WH 700 Lymphatic system. Lymphatic diseases (General)
Faculty: Department: Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI): https://doi.org/10.1093/cid/ciab191
Depositing User: Samantha Sheldrake
Date Deposited: 27 May 2021 15:33
Last Modified: 04 Jun 2021 10:25
URI: https://archive.lstmed.ac.uk/id/eprint/17955

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