Effect of sustained insecticide-treated bed net use on all-cause child mortality in an area of intense perennial malaria transmission in Western Kenya

Eisele, T. P., Lindblade, K. A., Wannemuehler, K. A., Gimnig, J. E., Odhiambo, F., Hawley, W. A., terKuile, Feiko ORCID: https://orcid.org/0000-0003-3663-5617, Phillips-Howard, P., Rosen, D. H., Nahlen, B. L., Vulule, J. M. and Slutsker, L. (2005) 'Effect of sustained insecticide-treated bed net use on all-cause child mortality in an area of intense perennial malaria transmission in Western Kenya'. American Journal of Tropical Medicine and Hygiene, Vol 73, Issue 1, pp. 149-156.

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Abstract

We present results from a study conducted in western Kenya where all-cause child mortality was assessed among a population with high levels of sustained insecticide-treated bed net (ITN) use for up to six years. Although ITNs were associated with significant reductions in all-cause mortality among infants 1-11 months old, there was no difference in the rate of all-cause mortality among children 12-59 months old with ITNs for 2-4 years, compared historically with children from villages without ITNs, after controlling for seasonality and underlying child mortality across calendar years (adjusted hazard ratio [AHR] = 0.91, 95% confidence interval [CI] = 0.77-1.07). There was no increase in the proportion of child deaths at older ages (1.2-59 months old) of all child deaths within villages with ITNs for 5-6 years (48.1%) compared historically with villages without ITNs (47.9%), after controlling for seasonality (AHR - 1.03, P = 0.834). We find no evidence that sustained ITN use increased the risk of mortality in older children in this area of intense perennial malaria transmission.

Item Type:	Article
Uncontrolled Keywords:	plasmodium-falciparum transmission randomized controlled-trial young-children impregnated bednets follow-up morbidity curtains immunity impact efficacy
Subjects:	QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control WS Pediatrics > By Age Groups > WS 430 Infancy WS Pediatrics > By Age Groups > WS 440 Preschool child
Depositing User:	Ms Julia Martin
Date Deposited:	16 Dec 2011 10:33
Last Modified:	07 Jun 2018 14:48
URI:	https://archive.lstmed.ac.uk/id/eprint/1833

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