LSTM Home > LSTM Research > LSTM Online Archive

Comparison of community-led distribution of HIV self-tests kits with distribution by paid distributors: a cluster randomised trial in rural Zimbabwean communities

Sibanda, Euphemia ORCID: https://orcid.org/0000-0003-1754-1076, Mangenah, Collin, Neuman, Melissa, Tumushime, Mary, Watadzaushe, Constancia, Mutseta, Miriam N, Maringwa, Galven, Dirawo, Jeffrey, Fielding, Katherine L, Johnson, Cheryl, Ncube, Getrude, Taegtmeyer, Miriam ORCID: https://orcid.org/0000-0002-5377-2536, Hatzold, Karin, Corbett, Elizabeth Lucy, Terris-Prestholt, Fern and Cowan, Frances ORCID: https://orcid.org/0000-0003-3087-4422 (2021) 'Comparison of community-led distribution of HIV self-tests kits with distribution by paid distributors: a cluster randomised trial in rural Zimbabwean communities'. BMJ Global Health, Vol 6, Issue Suppl_4, e005000.

[img]
Preview
Text
bmjgh-2021-005000.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial.

Download (3MB) | Preview

Abstract

Background: We compared community-led versus an established community-based HIV self-testing (HIVST) model in rural Zimbabwe using a cluster-randomised trial. Methods: Forty village groups were randomised 1:1 using restricted randomisation to community-led HIVST, where communities planned and implemented HIVST distribution for 4 weeks, or paid distribution (PD), where distributors were paid US$50 to distribute kits door-to-door over 4 weeks. Individual level primary outcomes compared household survey responses by arm 4 months post-intervention for: (1) newly diagnosed HIV during/within 4 months following HIVST distribution, (2) linkage to confirmatory testing, pre-exposure prophylaxis or voluntary medical male circumcision during/within 4 months following HIVST distribution. Participants were not masked to allocation; analysis used masked data. Trial analysis used random-effects logistic regression. Distribution costs compared: (1) community-led HIVST, (2) PD HIVST and (3) PD costs when first implemented in 2016/2017. Results: From October 2018 to August 2019, 27 812 and 36 699 HIVST kits were distributed in community-led and PD communities, respectively. We surveyed 11 150 participants and 5683 were in community-led arm. New HIV diagnosis was reported by 211 (3.7%) community-led versus 197 (3.6%) PD arm participants, adjusted OR (aOR) 1.1 (95% CI 0.72 to 1.56); 318 (25.9%) community-led arm participants linked to post-test services versus 361 (23.9%) in PD arm, aOR 1.1 (95% CI 0.75 to 1.49. Cost per HIVST kit distributed was US$6.29 and US$10.25 for PD and community-led HIVST, both lower than 2016/2017 costs for newly implemented PD (US$14.52). No social harms were reported. Conclusions: Community-led HIVST can perform as well as paid distribution, with lower costs in the first year. These costs may reduce with programme maturity/learning. Trial registration number: PACTR201811849455568.

Item Type: Article
Subjects: W General Medicine. Health Professions > W 74 Medical economics. Health care costs
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.1 Diagnosis
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.6 Prevention and control
Faculty: Department: Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI): https://doi.org/10.1136/bmjgh-2021-005000
SWORD Depositor: JISC Pubrouter
Depositing User: Stacy Murtagh
Date Deposited: 22 Jul 2021 12:30
Last Modified: 22 Jul 2021 12:30
URI: https://archive.lstmed.ac.uk/id/eprint/18459

Statistics

View details

Actions (login required)

Edit Item Edit Item