SARS-CoV-2 neutralising antibodies in dogs and cats in the United Kingdom

Smith, Shirley L., Anderson, Enyia, Cansado-Utrilla, Cintia, Prince, Tessa, Farrell, Sean, Brant, Bethaney, Smyth, Steven, Noble, Peter-John M., Pinchbeck, Gina L., Marshall, Nikki, Roberts, Larry, Hughes, Grant ORCID: https://orcid.org/0000-0002-7567-7185, Radford, Alan D. and Patterson, Ian ORCID: https://orcid.org/0000-0003-3465-0848 (2021) 'SARS-CoV-2 neutralising antibodies in dogs and cats in the United Kingdom'. Current Research in Virological Science, Vol 2, p. 100011.

Preview

Text SARS-CoV-2-neutralising-antibodies-in-dogs-and_2021_Current-Research-in-Viro GHughes Sept 21.pdf - Published Version Available under License Creative Commons Attribution. Download (622kB) | Preview

Abstract

Companion animals are susceptible to SARS-CoV-2 infection and sporadic cases of pet infections have occurred in the United Kingdom. Here we present the first large-scale serological survey of SARS-CoV-2 neutralising antibodies in dogs and cats in the UK. Results are reported for 688 sera (454 canine, 234 feline) collected by a large veterinary diagnostic laboratory for routine haematology during three time periods; pre-COVID-19 (January 2020), during the first wave of UK human infections (April–May 2020) and during the second wave of UK human infections (September 2020–February 2021). Both pre-COVID-19 sera and those from the first wave tested negative. However, in sera collected during the second wave, 1.4% (n ​= ​4) of dogs and 2.2% (n ​= ​2) of cats tested positive for neutralising antibodies. The low numbers of animals testing positive suggests pet animals are unlikely to be a major reservoir for human infection in the UK. However, continued surveillance of in-contact susceptible animals should be performed as part of ongoing population health surveillance initiatives.

Item Type:	Article
Subjects:	QW Microbiology and Immunology > Viruses > QW 160 Viruses (General). Virology QW Microbiology and Immunology > Antigens and Antibodies. Toxins and Antitoxins > QW 575 Antibodies
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.crviro.2021.100011
Depositing User:	Mel Finley
Date Deposited:	21 Sep 2021 12:58
Last Modified:	21 Sep 2021 13:00
URI:	https://archive.lstmed.ac.uk/id/eprint/18981

Statistics

View details

Actions (login required)

Edit Item