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Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans

Munks, R. J. L., Sant'Anna, Mauricio R.V., Grail, W., Gibson, W., Igglesden, T., Yoshiyama, M., Lehane, Stella and Lehane, Mike (2005) 'Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans'. Insect Molecular Biology, Vol 14, Issue 5, pp. 483-491.

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We report the characterization of 11 antioxidant genes from the tsetse fly Glossina m. morsitans. Through similarity searches which detected homology we suggest that these genes consist of two superoxide dismutases (one with a putative signal peptide), three thioredoxin peroxidases (one with a putative signal peptide), three peroxiredoxins, one further signal peptide-containing peroxidase with its closest similarity to a glutathione peroxidase, one catalase and one thioredoxin reductase. We describe the changes occurring in the expression levels of these genes during fly development, in different adult tissues, in the adult midgut through the digestive cycle and following trypanosome infection. Overall, nine of the 11 genes studied showed responses to changes in physiological circumstance, with the peroxiredoxin group showing the smallest variations throughout.

Item Type: Article
Uncontrolled Keywords: glossina antioxidant trypanosome immunity haem drosophila-melanogaster bloodsucking insect anopheles-gambiae tsetse-fly superoxide-dismutase stomoxys-calcitrans midgut sequence
Subjects: QU Biochemistry > Genetics > QU 450 General Works
QX Parasitology > Insects. Other Parasites > QX 505 Diptera
Faculty: Department: Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI):
Depositing User: Ms Julia Martin
Date Deposited: 30 Aug 2011 14:22
Last Modified: 17 Jul 2020 10:57


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