On Prioritising Global Health’s Triple Crisis of Sepsis, COVID-19 and Antimicrobial Resistance: A mixed-methods study from Malawi

Kawale, Paul, Kalitsilo, Levi, Mphande, Jessie, Adegbite, Bayode Romeo, Grobusch, Martin, Jacob, Shevin ORCID: https://orcid.org/0000-0003-2425-9394, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611 and Madise, Nyovani (2022) 'On Prioritising Global Health’s Triple Crisis of Sepsis, COVID-19 and Antimicrobial Resistance: A mixed-methods study from Malawi'. BMC Health Services Research, Vol 22, e613.

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Abstract

Sepsis causes 20% of global deaths, particularly among children and vulnerable populations living in developing countries. This study investigated how sepsis is prioritised in Malawi’s health system to inform health policy. In this mixed-methods study, twenty multisectoral stakeholders were qualitatively interviewed and asked to quantitatively rate the likelihood of sepsis-related medium-term policy outcomes being realised. Respondents indicated that sepsis is not prioritised in Malawi due to a lack of local sepsis-related evidence and policies. However, they highlighted strong linkages between sepsis and maternal health, antimicrobial resistance and COVID-19, which are already existing national priorities, and offers opportunities for sepsis researchers as policy entrepreneurs. To address the burden of sepsis, we recommend that funding should be channelled to the generation of local evidence, evidence uptake, procurement of resources and treatment of sepsis cases, development of appropriate indicators for sepsis, adherence to infection prevention and control measures, and antimicrobial stewardship.

Item Type:	Article
Subjects:	QW Microbiology and Immunology > QW 45 Microbial drug resistance. General or not elsewhere classified. WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 240 Bacteremia. Sepsis. Toxemias WC Communicable Diseases > Virus Diseases > Viral Respiratory Tract Infections. Respirovirus Infections > WC 506 COVID-19
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1186/s12913-022-08007-0
Depositing User:	Amy Smith
Date Deposited:	11 May 2022 09:43
Last Modified:	11 May 2022 09:43
URI:	https://archive.lstmed.ac.uk/id/eprint/20392

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