What the snake leaves in its wake: Functional limitations and disabilities among snakebite victims in Ghanaian communities

Aglanu, Leslie Mawuli, Amuasi, John Humphrey, Schut, Bob A., Steinhorst, Jonathan, Beyuo, Alexis, Dari, Chrisantus Danaah, Agbogbatey, Melvin Katey, Blankson, Emmanuel Steve, Punguyire, Damien, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Blessmann, Jörg, Abass, Kabiru Mohammed, Harrison, Robert and Stienstra, Ymkje (2022) 'What the snake leaves in its wake: Functional limitations and disabilities among snakebite victims in Ghanaian communities'. PLoS Neglected Tropical Diseases, Vol 16, Issue 5, e0010322.

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Abstract

Background: The estimated five million snakebites per year are an important health problem that mainly affect rural poor populations. The global goal is to halve both mortality and morbidity from this neglected tropical disease by 2030. Data on snakebite morbidity are sparse and mainly obtained from hospital records.
Methods: This community-based study was conducted among 379 rural residents with or without a history of snakebite in the Ashanti and Upper West regions of Ghana. All participants in the snakebite group were bitten at least six months before the day of survey. The World Health Organisation Disability Assessment Schedule 2.0 (WHODAS 2.0) and the Buruli Ulcer Functional Limitation Score were used to obtain patient-reported measure of functioning and disability. Long-term consequences were evaluated based on the severity of the symptoms at the time of the snakebite.
Findings: The median (IQR) time since the snakebite was 8.0 (3.5–16.5) years. The relative risk of disability was 1.54 (95% CI, 1.17–2.03) in the snakebite group compared to the community controls. Among patients with clinical symptoms suggesting envenoming at the time of bite, 35% had mild/moderate disabilities compared to 20% in the control group. The disability domains mainly affected by snakebite envenoming were cognition level, mobility, life activities and participation in society. A combination of the severity of symptoms at the time of the bite, age, gender and region of residence most accurately predicted the odds of having functional limitations and disabilities.
Conclusion: The burden of snakebite in the community includes long-term disabilities of mild to moderate severity, which need to be considered when designing appropriate public health interventions. Estimating the total burden of snakebite is complicated by geographic differences in types of snakes and their clinical manifestations.

Item Type:	Article
Subjects:	WA Public Health > WA 20.5 Research (General) WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Animal Poisons > WD 410 Reptiles
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1371/journal.pntd.0010322
SWORD Depositor:	JISC Pubrouter
Depositing User:	JISC Pubrouter
Date Deposited:	08 Sep 2022 13:42
Last Modified:	06 Jun 2023 16:35
URI:	https://archive.lstmed.ac.uk/id/eprint/20522

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