Respiratory syncytial virus and metapneumovirus in children over two seasons with a high incidence of respiratory infections in Brazil

Serafino, R.L, Gurgel, R. Q., Dove, W., Hart, C. Anthony and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2004) 'Respiratory syncytial virus and metapneumovirus in children over two seasons with a high incidence of respiratory infections in Brazil'. Annals of Tropical Paediatrics, Vol 24, Issue 3, pp. 213-217.

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Abstract

Acute respiratory infections (ARI) are one of the most important causes of death in children. Human metapneumovirus (HMPV), a virus first described in 200 1, has now been detected in almost all continents. HMPV causes bronchiolitis and pneumonia with a clinical spectrum similar to respiratory syncytial virus (RSV). We describe the incidence of HMPV and RSV during two consecutive seasons with a high incidence of ARI in Aracaju, Brazil. HMPV was responsible for 24% of cases of bronchiolitis in the 1st season (April-May 2002) but was not found in the 2nd year (April-May 2003). RSV was recovered from 61 (55%) children with ARI in 2002 and from 72 (68%) in 2003. Children with RSV bronchiolitis in 2002 had more hypoxia but less wheezing than in 2003. The incidence of HMPV and RSV genotypes causing bronchiolitis varied between the years. Long-term prospective studies are required to better describe the epidemiology of these viruses in children.

Item Type:	Article
Uncontrolled Keywords:	group-a group-b disease severity young-children united-states subgroup-a bronchiolitis genotype illness manifestations
Subjects:	WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 202 Pneumonia (General or not elsewhere classified) WS Pediatrics > WS 20 Research (General) WS Pediatrics > Diseases of Children and Adolescents > By System > WS 280 Respiratory system
Faculty: Department:	Groups (2002 - 2012) > Child & Reproductive Health Group
Digital Object Identifer (DOI):	https://doi.org/10.1179/027249304225018957
Depositing User:	Sarah Lewis-Newton
Date Deposited:	29 Mar 2012 16:34
Last Modified:	06 Feb 2018 13:03
URI:	https://archive.lstmed.ac.uk/id/eprint/2119

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