Anthropometric, biochemical, dietary, morbidity and wellbeing assessments in women and children in Indonesia, India and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper

Davies-Kershaw, Hilary, Fahmida, Umi, Kyaw Htet, Min, Kulkarni, Bharati, Faye, Babacar, Yanti, Dwi, Shinta, Dewi, Lailatuz Zahra, Nur, Cornelia Angelin, Tiffany, Madhari, Radhika, Pullakhandam, Raghu, Palika, Ravindranadh, Rajeev, Teena, Fernandez Rao, Sylvia, Kumar Banjara, Santosh, Selvaraj, Kiruthika, Pratyusha, Dharani, Yadav, Dinesh, Diouf, Saliou, Lopez-Sall, Philomène, Diallo, Babacar, Mouissi, Princillia, Fall, Sally, Diallo, Ibrahima, Djigal, Aicha, Van Immerzeel, Tabitha, Tairou, Fassia, Diop, Assana, Pradeilles, Rebecca, Strout, Sara, Kadia, Benjamin, Tetsa Tata, Darius, Lamin Jobarteh, Modou, Allen, Stephen ORCID: https://orcid.org/0000-0001-6675-249X, Walker, Alan, Webster, Joanne, Haggarty, Paul, Heffernan, Claire and Ferguson, Elaine (2024) 'Anthropometric, biochemical, dietary, morbidity and wellbeing assessments in women and children in Indonesia, India and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper'. BMJ Paediatrics Open, Vol 8, Issue S1, e001683.

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Abstract

Introduction:
Child-stunting has a complex aetiology, especially in the first 1000 days of life. Nutrition interventions alone have not produced expected impacts in reducing/preventing child-stunting, indicating the importance of understanding the complex interplay between environmental, physiological and psychological factors influencing child nutritional status.
This study will investigate maternal and child nutrition, health and wellbeing status and associated factors through the assessment of:(1) anthropometry; (2) biomarkers of nutrition and health status; (3) dietary intakes; (4) fetal growth and development; (5) infant morbidity; (6) Infant and Young Child Feeding (IYCF); and (7) perinatal maternal stress, depression and social support.

Methods:
This study will be conducted in a prospective pregnancy cohort in India, Indonesia and Senegal. Pregnant women will be recruited in the second (Indonesia, Senegal) and third (India) trimester of pregnancy, and the mother and infant dyads followed until the infant is 24-months of age. During pregnancy, anthropometric measures will be taken, venous blood samples will be collected for biochemical assessment of nutrition and health status, dietary intakes will be assessed using a 4-pass-24-hour dietary recall method (MP24HR), fetal ultrasound for assessment of fetal growth. After birth, anthropometry measurements will be taken, venous blood samples will be collected, MP24HR will be conducted, infant morbidity and IYCF practices will be assessed and a sample of breastmilk will be collected for nutrient composition analyses. Perinatal maternal stress, depression, social support and hair cortisol levels (stress) will be measured. The results from this study will be integrated in an interdisciplinary analysis to examine factors influencing infant growth and inform global efforts in reducing child stunting.

Ethics and dissemination:
Ethical approval was granted by the Ethics Committee of the London School of Hygiene and Tropical Medicine (17915/RR/17513); National Institute of Nutrition (ICMR)- Ministry of Health and Family Welfare, Government of India (CR/04/I/2021); Health Research Ethics Committee, University of Indonesia and Cipto Mangunkusumo Hospital (KET-887/UN2.F1/ETIK/PPM.00.02/2019); and the Comité National d'Ethique pour la Recherche en Santé, Senegal (Protocole SEN19/78); the Royal Veterinary College (URN SR2020-0197); and the International Livestock Research Institute Institutional Research Ethics Committee (ILRI-IREC2020-33). Results will be published in peer-reviewed journals and disseminated to policy makers and participating communities.

Item Type:	Article
Subjects:	QU Biochemistry > QU 4 General works WA Public Health > Health Problems of Special Population Groups > WA 309 Women's health WA Public Health > Health Problems of Special Population Groups > WA 320 Child Welfare. Child Health Services. WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Nutrition Disorders > WD 100 General works
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1136/bmjpo-2022-001683
Depositing User:	Rachel Dominguez
Date Deposited:	16 May 2023 11:37
Last Modified:	19 Mar 2024 15:57
URI:	https://archive.lstmed.ac.uk/id/eprint/22391

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