Acceptability of azithromycin for the control of trachoma in Northern Tanzania

Desmond, Nicola ORCID: https://orcid.org/0000-0002-2874-8569, Solomon, Anthony W., Massae, Patrick A., Lema, Ndeeshi, Anemona, Alessandra, Foster, Allen and Mabey, David C.W. (2005) 'Acceptability of azithromycin for the control of trachoma in Northern Tanzania'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 99, Issue 9, pp. 656-663.

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Abstract

Trachoma causes blindness; the prevention strategy includes mass antibiotic treatment. In a community in Northern Tanzania offered mass treatment with azithromycin for the control of trachoma, we used focus group discussions, individual interviews, questionnaires and direct observation to quantify, explore and contextualize reasons for acceptance or refusal of the drug. In the village studied, 76% of the population eligible to receive azithromycin were treated. Uptake was significantly higher among women (79% treated) than men (72%). Factors affecting acceptability included: local prevention norms (such as the belief that injections, rather than oral medicine, should be used for prevention); perceptions of drugs in general and azithromycin in particular; perceptions of the distribution team’s expertise; witnessing adverse effects in others; and the timing, quality and quantity of information about azithromycin and its availability. Familiarity with trachoma as a blinding disease was significantly associated with uptake. Individuals who refused treatment seemed to be less altruistic than other respondents. Neither socio-economic status nor use of traditional healers was related to uptake. Pre-distribution community assessment and community education, advance notice of the distribution, standardized distribution guidelines and improved distributor training are recommended to maximize acceptance of azithromycin in future campaigns.

Item Type:	Article
Uncontrolled Keywords:	NOT_LSTM
Subjects:	WW Ophthalmology > Eye Structures and their Diseases > WW 215 Trachoma WW Ophthalmology > Eye Structures and their Diseases > WW 276 Blindness. Amblyopia
Faculty: Department:	Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.trstmh.2005.03.006
Depositing User:	Rachel Dominguez
Date Deposited:	22 Jun 2023 13:47
Last Modified:	27 Jun 2023 10:53
URI:	https://archive.lstmed.ac.uk/id/eprint/22684

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