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Marriott, Amy, Casewell, Nicholas R, Lilley, Elliot, Gutiérrez, José-María and Ainsworth, Stuart 
ORCID: https://orcid.org/0000-0002-0199-6482
(2024)
'Improving in vivo assays in snake venom and antivenom research: A community discussion'. F1000Research, Vol 13, p. 192.
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SnakeVenomF1000Researchpaper_amy_marriott.pdf - Published Version Available under License Creative Commons Attribution. Download (380kB) | Preview |
Abstract
On the 26th January 2023, a free to attend, ‘improving in vivo snake venom research: a community discussion’ meeting was held virtually. This webinar brought together researchers from around the world to discuss current neutralisation of venom lethality mouse assays that are used globally to assess the efficacy of therapies for snakebite envenoming. The assay’s strengths and weaknesses were highlighted, and we discussed what improvements could be made to refine and reduce animal testing, whilst supporting preclinical antivenom and drug discovery for snakebite envenoming. This report summarises the issues highlighted, the discussions held, with additional commentary on key perspectives provided by the authors.
| Item Type: | Article |
|---|---|
| Subjects: | QW Microbiology and Immunology > Antigens and Antibodies. Toxins and Antitoxins > QW 630 Toxins. Antitoxins WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Animal Poisons > WD 410 Reptiles |
| Faculty: Department: | Biological Sciences > Department of Tropical Disease Biology |
| Digital Object Identifer (DOI): | https://doi.org/10.12688/f1000research.148223.1 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 28 Mar 2024 09:04 |
| Last Modified: | 28 Mar 2024 09:04 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/24251 |
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