Elevated plasma von Willebrand factor and propeptide levels in malawian children with malaria.

Phiri, Happy T, Bridges, Daniel J, Glover, Simon J, van Mourik, Jan A, de Laat, Bas, M'baya, Bridon, Taylor, Terrie E, Seydel, Karl B, Molyneux, Malcolm E, Faragher, Brian, Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 and Bunn, J. (2011) 'Elevated plasma von Willebrand factor and propeptide levels in malawian children with malaria.'. PLoS ONE, Vol 6, Issue 11, e25626.

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Abstract

In children with malaria plasma VWF and propeptide levels are markedly elevated in both cerebral and mild paediatric malaria, with levels matching disease severity, and these normalize upon recovery. High levels of both markers also occur in retinopathy-negative 'cerebral malaria' cases, many of whom are thought to be suffering from diseases other than malaria, indicating that further studies of these markers will be required to determine their sensitivity and specificity.

Item Type:	Article
Subjects:	WH Hemic and Lymphatic Systems > WH 100 General works WH Hemic and Lymphatic Systems > WH 20 Research (General) WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 322 Blood coagulation disorders (General) WS Pediatrics > WS 100 General works WS Pediatrics > WS 20 Research (General)
Digital Object Identifer (DOI):	https://doi.org/10.1371/journal.pone.0025626
Depositing User:	Mary Creegan
Date Deposited:	06 Dec 2011 16:04
Last Modified:	17 Aug 2022 08:56
URI:	https://archive.lstmed.ac.uk/id/eprint/2456

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