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Devine, G. J., Perea, E. Z., Killeen, Gerry 
ORCID: https://orcid.org/0000-0002-8583-8739, Stancil, J. D., Clark, S. J. and Morrison, A. C.
(2009)
'Using adult mosquitoes to transfer insecticides to Aedes aegypti larval habitats'. Proceedings of the National Academy of Sciences of the United States of America, Vol 106, Issue 28, pp. 11530-11534.
Abstract
Vector control is a key means of combating mosquito-borne diseases and the only tool available for tackling the transmission of dengue, a disease for which no vaccine, prophylaxis, or therapeutant currently exists. The most effective mosquito control methods include a variety of insecticidal tools that target adults or juveniles. Their successful implementation depends on impacting the largest proportion of the vector population possible. We demonstrate a control strategy that dramatically improves the efficiency with which high coverage of aquatic mosquito habitats can be achieved. The method exploits adult mosquitoes as vehicles of insecticide transfer by harnessing their fundamental behaviors to disseminate a juvenile hormone analogue (JHA) between resting and oviposition sites. A series of field trials undertaken in an Amazon city (Iquitos, Peru) showed that the placement of JHA dissemination stations in just 3-5% of the available resting area resulted in almost complete coverage of sentinel aquatic habitats. More than control mortality occurred in 95-100% of the larval cohorts of Aedes aegypti developing at those sites. Overall reductions in adult emergence of 42-98% were achieved during the trials. A deterministic simulation model predicts amplifications in coverage consistent with our observations and highlights the importance of the residual activity of the insecticide for this technique.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | dengue innovation vector control auto-dissemination juvenile hormone analogue GROWTH-REGULATOR PYRIPROXYFEN ANOPHELES-GAMBIAE CULICIDAE PRODUCTION TREATED BEDNETS DENGUE VECTORS DIPTERA MALARIA DISPERSAL IQUITOS AFRICA |
| Subjects: | WC Communicable Diseases > Virus Diseases > Infectious Mononucleosis. Arbovirus Infections > WC 528 Dengue QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes QX Parasitology > Insects. Other Parasites > QX 525 Aedes |
| Faculty: Department: | Groups (2002 - 2012) > Vector Group |
| Digital Object Identifer (DOI): | https://doi.org/10.1073/pnas.0901369106 |
| Depositing User: | Users 183 not found. |
| Date Deposited: | 14 Jun 2010 10:37 |
| Last Modified: | 16 Sep 2019 10:12 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/252 |
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