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Wang, Jinbang, Zhou, Yunting, Liu, Yu, Sang, Miaomiao, Ding, Yuzhi, Li, Tingting, Wang, Xiaohang, Carvalho, Vladmir, Ni, Chengming, Wang, Qianqian, Cai, Zhensheng, Wang, Huan, Chen, Yang, Shang, Zhanjia, Wang, Duolao 
ORCID: https://orcid.org/0000-0003-2788-2464, Qiu, Shanhu and Sun, Zilin
(2024)
'Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study'. BMC Endocrine Disorders, Vol 24, Issue 1, e231.
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12902_2024_Article_1721.pdf - Published Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (1MB) | Preview |
Abstract
Aims
Night blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.
Methods
This multi-center, cross-sectional study enrolled a total of 5664 participants aged 18–82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.
Results
A total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.
Conclusions
The results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.
| Item Type: | Article |
|---|---|
| Subjects: | QU Biochemistry > Vitamins > QU 160 Vitamins. Vitamin requirements WK Endocrine System > WK 835 Complications of diabetes WW Ophthalmology > Diseases. Color Perception > WW 141 Examination. Diagnosis. Diagnostic methods (General). Monitoring Vision disorders (General) |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1186/s12902-024-01721-2 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 11 Nov 2024 09:29 |
| Last Modified: | 11 Nov 2024 09:29 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/25533 |
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