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Solarin, Ijeoma, Dumbura, Cherlynn, Lakhoo, Darshnika Pemi, Chande, Kshama, Maimela, Gloria, Luchters, Stanley and Chersich, Matthew (2024) 'Characteristics of longitudinal maternal health studies in sub‐Saharan Africa: A systematic mapping of literature between 2012 and 2022'. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. (In Press)
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Abstract
Background
High maternal mortality rates in sub-Saharan Africa necessitate the need for aligned research focusing on prevalent causes and neglected conditions in the region.
Objective
This mapping review aimed to describe the characteristics of longitudinal maternal health studies between 2012 and 2022 in sub-Saharan Africa and identify gaps in priority conditions or geographical locations.
Search Strategy
We identified references through a Medline (PubMed) search covering September 2012 to June 2022.
Selection Criteria
We included prospective cohort or clinical trials that enrolled at least 1000 pregnant women, with a study site in sub-Saharan Africa, and published in English or French.
Data Collection and Analysis
Screening and data extraction were done in duplicate using EPPI-reviewer software. Descriptive analysis was used to summarize the results, identifying patterns in studies across time, country, study design, topics, and funders.
Main Results
We identified 213 eligible studies, which were covered in 534 publications. We identified studies in 33 of the 48 sub-Saharan African countries, with the majority in east and southern Africa. The predominant study topics were HIV (36.4%), nutrition (20%), and malaria (16.3%), with very few publications on hypertensive disorders of pregnancy (6.4%), ante/postpartum hemorrhage (3.7%), and sexually transmitted infections (3.2%). More studies were cohorts (115/213; 54%) than clinical trials. The National Institutes of Health (31.5%), Bill and Melinda Gates Foundation (22.1%), and USAID (10.8%) were the largest research funders.
Conclusion
Identifying research trends and mismatches between research topics and disease burden provides useful information for guiding future research prioritization. In particular, gaps exist for studies on hypertensive disorders of pregnancy and ante/postpartum hemorrhage, among the top causes of maternal mortality in sub-Saharan Africa.
| Item Type: | Article |
|---|---|
| Corporate Authors: | HE2AT Center |
| Subjects: | WA Public Health > Health Problems of Special Population Groups > WA 310 Maternal welfare |
| Faculty: Department: | Clinical Sciences & International Health > International Public Health Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1002/ijgo.16035 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 02 Dec 2024 10:19 |
| Last Modified: | 02 Dec 2024 10:19 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/25627 |
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