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Veiga, Rafael V., Cunha, Sergio S., Dattoli, Vitor C. C., Cruz, Álvaro C., Cooper, Philip, Rodrigues, Laura C., Barreto, Maurício L. and Alcantara-Neves, Neuza M. (2011) 'Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.'. BMC pulmonary medicine, Vol 11, Issue 24.
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Cooper-BMC-12.pdf - Published Version Download (243kB) |
Abstract
These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.
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