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Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.

Fatih, Farrah A, Siner, Angela, Ahmed, Atique, Woon, Lu Chan, Craig, Alister ORCID:, Singh, Balbir, Krishna, Sanjeev and Cox-Singh, Janet (2012) 'Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.'. Malaria Journal, Vol 11, p. 33.

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Plasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM. Binding to the constitutively-expressed endothelial receptor CD36 was not detected. Further work will be required to define the pathological consequences of these interactions.

Item Type: Article
Uncontrolled Keywords: P. knowlesi Cytoadherence SICAvar ICAM-1 VCAM CD36 Malaria Coma
Subjects: QX Parasitology > Protozoa > QX 135 Plasmodia
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 150 Erythrocytes
Faculty: Department: Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group
Digital Object Identifer (DOI):
Depositing User: Mary Creegan
Date Deposited: 31 Jul 2012 13:01
Last Modified: 17 Jul 2019 14:14


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