Treatment of intestinal parasitic infections: a review of nitazoxanide

Gilles, Herbert M and Hoffman, Paul S (2002) 'Treatment of intestinal parasitic infections: a review of nitazoxanide'. Trends in Parasitology, Vol 18, Issue 3, pp. 95-97.

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Abstract

Intestinal parasitic infections rank among the most significant causes of morbidity and mortality in the world, yet economic and other factors have contributed to a lack of innovation in treating these diseases. Nitazoxanide, a pyruvate ferredoxin oxidoreductase inhibitor, is a new antiparasitic drug notable for its activity in treating protozoan infections, including Cryptosporidium, which cause persistent diarrhoea and malnutrition in children throughout the developing world. Importantly, studies have shown that nitazoxanide is also effective in treating common intestinal helminths. The availability of a product with this spectrum of activity raises interesting new possibilities for treating intestinal parasitic infections.

Item Type:	Article
Subjects:	QV Pharmacology > Dermatologic Agents. Gastrointestinal Agents > QV 66 Gastrointestinal agents QX Parasitology > QX 4 General works WC Communicable Diseases > Tropical and Parasitic Diseases > WC 698 Parasitic intestinal diseases (General)
Faculty: Department:	Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI):	https://doi.org/10.1016/s1471-4922(01)02205-x
Depositing User:	Users 476 not found.
Date Deposited:	26 Nov 2012 11:20
Last Modified:	06 Feb 2018 13:05
URI:	https://archive.lstmed.ac.uk/id/eprint/2922

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