LSTM Home > LSTM Research > LSTM Online Archive

Clostridium difficile Toxin in Adult Inpatients in an Urban Hospital in Malawi: Associations with HIV Status, CD4 Count and Diarrhoea

Beadsworth, Michael, Keeley, Alex J., Roberts, Paul, Faragher, Brian, Watson, Alastair and Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791 (2014) 'Clostridium difficile Toxin in Adult Inpatients in an Urban Hospital in Malawi: Associations with HIV Status, CD4 Count and Diarrhoea'. International Journal of Tropical Medicine, Vol 9, Issue 1, pp. 7-9.

Full text not available from this repository.

Abstract

Clostridium difficile Infection (CDI) is the cause of substantial morbidity and mortality in the developed world. However, very little is known about the burden of CDI in sub-Saharan Africa where less antibiotic restriction, high HIV prevalence and greater impact from nosocomial infection mean the potential for a significant disease burden is great. Researchers investigated the prevalence of Clostridium difficile Toxin (CDT), assessing association with HIV, CD4 count and diarrhoea in medical in-patients in Malawi. In 206 patients tested for CDT, 28 (13.6%) were positive. No significant associations were seen with either diarrhoea or HIV. There was a non-statistically significant (p = 0.056) association between CD4 counts of <50 and CDT. The frequency and the clinical implications of CDI in both HIV positive and negative patients in sub-Saharan Africa, requires further assessment.

Item Type: Article
Subjects: WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Infection. Bacterial Infections > Other Bacterial Infections. Zoonotic Bacterial Infections > WC 368 Clostridium infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WI Digestive System > WI 407 Diarrhea
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.3923/ijtmed.2014.7.9
Depositing User: Lynn Roberts-Maloney
Date Deposited: 22 Jun 2015 09:21
Last Modified: 20 Nov 2024 15:07
URI: https://archive.lstmed.ac.uk/id/eprint/5219

Statistics

View details

Actions (login required)

Edit Item Edit Item