Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region

Bottomley, Christian, Wanji, Samuel, Amvongo-Adjia, Nathalie, Koudou, Benjamin, Njouendou, Abdel Jelil, Chounna Ndongmo, Patrick W., Kengne-Ouafo, Jonas A., Datchoua-Poutcheu, Fabrice R., Fovennso, Bridget Adzemye, Tayong, Dizzle Bita, Fombad, Fanny Fri, Fischer, Peter U., Enyong, Peter I. and Bockarie, Moses (2015) 'Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region'. PLoS Neglected Tropical Diseases, Vol 9, Issue 11, e0004184.

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Abstract

Background

Immunochromatographic card test (ICT) is a tool to map the distribution of Wuchereria bancrofti. In areas highly endemic for loaisis in DRC and Cameroon, a relationship has been envisaged between high L. loa microfilaria (Mf) loads and ICT positivity. However, similar associations have not been demonstrated from other areas with contrasting levels of L. loa endemicity. This study investigated the cross-reactivity of ICT when mapping lymphatic filariasis (LF) in areas with contrasting endemicity levels of loiasis and mansonellosis in Cameroon.

Item Type:	Article
Subjects:	QX Parasitology > Helminths. Annelida > QX 301 Filarioidea WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI):	https://doi.org/10.1371/journal.pntd.0004184
Depositing User:	Samantha Sheldrake
Date Deposited:	16 Dec 2015 14:50
Last Modified:	06 Feb 2018 13:11
URI:	https://archive.lstmed.ac.uk/id/eprint/5442

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