High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men—San Francisco, California

Hollingsworth, Deirdre, Pilcher, Christopher, Hecht, Frederick M, Deeks, Steven G and Fraser, Christophe (2014) 'High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men—San Francisco, California'. Journal of Infectious Disease, Vol 211, Issue 11, pp. 1757-1760.

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Abstract

We estimate the relative transmission rate in early versus later infection among men who have sex with men (MSM) in San Francisco, California, by studying the characteristics of a sample of transmitters, recruited through newly diagnosed, recently infected MSM between 1996 and 2009. Of 36 transmitters identified, 9 were determined on the basis of testing history and serologic testing to have been recently infected. The unadjusted odds ratio of transmitting during early infection was 15.2 (95% confidence interval [CI], 6.3–33.4; P < .001); the odds ratio was 8.9 (95% CI, 4.1–19.4) after adjustment for self-reported antiretroviral treatment. This high transmissibility could be due to both high infectiousness and high rates of sex partner change or concurrent partnerships.

Item Type:	Article
Subjects:	WA Public Health > Preventive Medicine > WA 110 Prevention and control of communicable diseases. Transmission of infectious diseases WA Public Health > Health Problems of Special Population Groups > WA 300 General. Refugees WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.3 Etiology. Transmission
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1093/infdis/jiu831
Depositing User:	Jessica Jones
Date Deposited:	11 Jan 2016 14:10
Last Modified:	07 Dec 2018 09:37
URI:	https://archive.lstmed.ac.uk/id/eprint/5473

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