Flow cytometry to assess CSF fungal burden in cryptococcal meningitis

Scriven, James, Graham, Lisa M, Schutz, Charlotte, Scriba, Thomas J, Wilkinson, Robert J, Boulware, David R, Meintjes, Graeme, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 and Urban, Britta ORCID: https://orcid.org/0000-0002-4197-8393 (2016) 'Flow cytometry to assess CSF fungal burden in cryptococcal meningitis'. Journal of Clinical Microbiology, Vol 54, Issue 3, pp. 802-804.

Preview	Text J_Clin_Micro_30_Dec_2015_Flowcytometry to assess CSF fungal burden.pdf - Accepted Version Available under License Creative Commons Attribution Non-commercial. Download (1MB) | Preview
Preview	Text J_Clin_Micro_54_3_802-804_Flow cytometry.pdf - Published Version Available under License Creative Commons Attribution Non-commercial. Download (766kB) | Preview

Abstract

Fungal burden in the cerebrospinal fluid is an important determinant of mortality in cryptococcal meningitis but its use to aid clinical decision-making is hampered by the time involved to perform quantitative cultures. Here we demonstrate the potential of flow cytometry as a novel and rapid technique to address this.

Item Type:	Article
Subjects:	QW Microbiology and Immunology > Fungi. Pathogenic Fungi. > QW 180 Pathogenic Fungi WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 245 Meningococcal infections WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.5 Complications WL Nervous System > WL 200 Meninges. Blood-brain barrier
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department Clinical Sciences & International Health > International Public Health Department Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1128/JCM.03002-15
Depositing User:	Jessica Jones
Date Deposited:	01 Feb 2016 13:37
Last Modified:	06 Feb 2018 13:11
URI:	https://archive.lstmed.ac.uk/id/eprint/5576

Statistics

View details

Actions (login required)

Edit Item