A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis

Nicol, Mark Patrick, Gnanashanmugam, Devasena, Browning, Renee, Click, Eleanor S, Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587, Detjen, Anne, Graham, Steve M, Levin, Michael, Makhene, Mamodikoe, Nahid, Payam, Perez-Velez, Carlos M, Reither, Klaus, Song, Rinn, Spiegel, Hans M L, Worrell, Carol, Zar, Heather J and Walzl, Gerhard (2015) 'A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis'. Clinical Infectious Diseases, Vol 61, Issue S3, S164-S172.

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Abstract

Childhood tuberculosis contributes significantly to the global tuberculosis disease burden but remains challenging to diagnose due to inadequate methods of pathogen detection in paucibacillary pediatric samples and lack of a child-specific host biomarker to identify disease. Accurately diagnosing tuberculosis in children is required to improve case detection, surveillance, healthcare delivery, and effective advocacy. In May 2014, the National Institutes of Health convened a workshop including researchers in the field to delineate priorities to address this research gap. This blueprint describes the consensus from the workshop, identifies critical research steps to advance this field, and aims to catalyze efforts toward harmonization and collaboration in this area.

Item Type:	Article
Subjects:	WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General) WF Respiratory System > Tuberculosis > WF 220 Diagnosis. Prognosis WF Respiratory System > Tuberculosis > WF 415 Tuberculosis in childhood WS Pediatrics > Diseases of Children and Adolescents > By System > WS 280 Respiratory system
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1093/cid/civ613
Depositing User:	Jessica Jones
Date Deposited:	11 Feb 2016 16:28
Last Modified:	15 Jun 2018 14:37
URI:	https://archive.lstmed.ac.uk/id/eprint/5619

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