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Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study

McCallum, Andrew, Nyirenda, Deborah, Lora, Wezzie, Khoo, Saye H., Sloan, Derek, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Desmond, Nicola ORCID: https://orcid.org/0000-0002-2874-8569 and Davies, Geraint R (2016) 'Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study'. PLoS ONE, Vol 11, Issue 10, e0165734.

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Abstract

Bronchoscopy is an established research tool in Malawi, enabling collection of pulmonary samples for immunological, pharmacological, and microbiological studies. It is, however, an invasive clinical procedure that offers no direct benefit to volunteering participants when used in a research capacity alone, and thus informed consent is essential. This study aimed to explore TB patients’ understanding of research bronchoscopy, what would motivate them to participate in research bronchoscopy, and their concerns, in order to inform consenting processes for future clinical studies. We used a qualitative research design. Two focus group discussions were conducted with community members and TB patients to understand their perceptions of bronchoscopy. Transcripts were coded by multiple co-authors and thematic content analysis was used to analyse main findings. We found that Malawian patients with pulmonary TB were willing to participate in a study using research bronchoscopy for health assessment and access to improved healthcare. We identified information of value to potential participants when consenting to that may lessen some of the anxieties expressed by participants. Patient and public involvement is essential to improve informed consent and institutional trust.

Item Type: Article
Subjects: W General Medicine. Health Professions > Health Services. Patients and Patient Advocacy > W 85 Patients. Attitude and compliance
WF Respiratory System > Tuberculosis > WF 300 Pulmonary tuberculosis
WO Surgery > Operative Surgical Procedures. Techniques > WO 500 General works on surgical procedures
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.1371/journal.pone.0165734
SWORD Depositor: JISC Pubrouter
Depositing User: JISC Pubrouter
Date Deposited: 31 Oct 2016 10:45
Last Modified: 12 Sep 2019 14:16
URI: https://archive.lstmed.ac.uk/id/eprint/6320

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