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Interventions to increase tuberculosis case detection at primary healthcare or community-level services

Mhimbira, Francis A, Cuevas, Luis ORCID:, Dacombe, Russell ORCID:, Mkopi, Abdallah and Sinclair, David (2017) 'Interventions to increase tuberculosis case detection at primary healthcare or community-level services'. Cochrane Database of Systematic Reviews, Vol 11, CD011432.

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Pulmonary tuberculosis is usually diagnosed when symptomatic individuals seek care at healthcare facilities, and healthcare workers have a minimal role in promoting the health-seeking behaviour. However, some policy specialists believe the healthcare system could be more active in tuberculosis diagnosis to increase tuberculosis case detection.

To evaluate the effectiveness of different strategies to increase tuberculosis case detection through improving access (geographical, financial, educational) to tuberculosis diagnosis at primary healthcare or community-level services.

We searched the following databases for relevant studies up to 19 December 2016: the Cochrane Infectious Disease Group Specialized Register; the Cochrane Central Register of Controlled Trials (CENTRAL), published in the Cochrane Library, Issue 12, 2016; MEDLINE; Embase; Science Citation Index Expanded, Social Sciences Citation Index; BIOSIS Previews; and Scopus. We also searched the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP),, and the metaRegister of Controlled Trials (mRCT) for ongoing trials.

Randomized and non-randomized controlled studies comparing any intervention that aims to improve access to a tuberculosis diagnosis, with no intervention or an alternative intervention.

Two review authors independently assessed trials for eligibility and risk of bias, and extracted data. We compared interventions using risk ratios (RR) and 95% confidence intervals (CI). We assessed the certainty of the evidence using the GRADE approach.

Item Type: Article
Subjects: WA Public Health > WA 20.5 Research (General)
WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General)
WF Respiratory System > Tuberculosis > WF 220 Diagnosis. Prognosis
WY Nursing > WY 106 Community health nursing
WY Nursing > WY 153 Communicable disease nursing
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):
SWORD Depositor: JISC Pubrouter
Depositing User: Stacy Murtagh
Date Deposited: 05 Dec 2017 13:11
Last Modified: 08 Dec 2020 14:02


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