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High utility of active tuberculosis case finding in an Ethiopian prison

Merid, Y., Woldeamanuel, Y., Abebe, M., Datiko, Daniel, Hailu, T., Habtamu, G., Assefa, G., Kempker, R. R., Blumberg, H. M. and Aseffa, A. (2018) 'High utility of active tuberculosis case finding in an Ethiopian prison'. International Journal of Tuberculosis and Lung Disease, Vol 22, Issue 5, pp. 524-529.

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SETTING: Hawassa Prison, Southern Region of Ethiopia.
OBJECTIVE: To determine the burden of pulmonary tuberculosis (TB) using active case finding among prisoners.
DESIGN: In this cross-sectional study, prisoners were screened for TB using a symptom screen. Those with cough of 2 weeks had spot and morning sputum samples collected for acid-fast bacilli (AFB) smear microscopy and molecular diagnostic testing (Xpert® MTB/RIF).
RESULTS: Among 2068 prisoners, 372 (18%) had a positive cough screen. The median age of these 372 persons was 23 years, 97% were male and 63% were from urban areas. Among those with a positive symptom screen, 8 (2%) were AFB sputum smear-positive and 31 (8%) were Xpert-positive. The point prevalence of pulmonary TB at the prison was 1748 per 100 000 persons. In multivariate analysis, persons with cough >4 weeks were more likely to have TB (OR 3.34, 95%CI 1.54–7.23).
CONCLUSION: A high prevalence of TB was detected among inmates at a large Ethiopian prison. Active case finding using a cough symptom screen in combination with Xpert had high utility, and has the potential to interrupt transmission of Mycobacterium tuberculosis in correctional facilities in low- and middle-income, high-burden countries.

Item Type: Article
Subjects: WA Public Health > WA 30 Socioeconomic factors in public health (General)
WF Respiratory System > WF 100 General works
WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General)
WF Respiratory System > Tuberculosis > WF 205 Epidemiology
WF Respiratory System > Tuberculosis > WF 205.1 General coverage
Digital Object Identifer (DOI):
SWORD Depositor: JISC Pubrouter
Depositing User: Stacy Murtagh
Date Deposited: 26 Apr 2018 14:11
Last Modified: 13 Jun 2023 12:29


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