Tools
Tools
Graves, Patricia, Gelband, Hellen, Garner, Paul 
ORCID: https://orcid.org/0000-0002-0607-6941 and Choi, Leslie
(2018)
'Gametocytocidal drugs: taking the population perspective.'. Lancet Infectious Diseases, Vol 18, Issue 7, p. 719.
Abstract
In their Article Dicko and colleagues1 state that both primaquine and methylene blue were “highly efficacious for preventing Plasmodium falciparum transmission” when given alongside primary malaria treatment, implying an effect on malaria transmission in the community. However, the trial measured the infectiousness of individuals to mosquitoes, which is several steps removed from the dynamics of disease transmission. Other trials have also measured whether individuals are less infectious to mosquitoes after treatment with a gametocytocidal agent, but none have measured an effect on transmission in the community, the outcome of real interest.
| Item Type: | Article |
|---|---|
| Subjects: | QV Pharmacology > Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > QV 256 Antimalarials WA Public Health > Preventive Medicine > WA 110 Prevention and control of communicable diseases. Transmission of infectious diseases WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.1016/S1473-3099(18)30337-2 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | Stacy Murtagh |
| Date Deposited: | 20 Jul 2018 14:07 |
| Last Modified: | 21 Nov 2019 15:24 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/8933 |
Statistics
Actions (login required)
 |
Edit Item |