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Precision mapping: An innovative tool and way forward to shrink the map, better target interventions, and accelerate toward the elimination of schistosomiasis

Tchuem Tchuenté, Louis-Albert, Stothard, Russell ORCID:, Rollinson, David and Reinhard-Rupp, Jutta (2018) 'Precision mapping: An innovative tool and way forward to shrink the map, better target interventions, and accelerate toward the elimination of schistosomiasis'. PLoS Neglected Tropical Diseases, Vol 12, Issue 8, e0006563.

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The mainstay of current schistosomiasis control is preventive chemotherapy (PC) with praziquantel, targeted toward school-aged children, based on the disease endemicity within a subset of surveyed schools, which are classified using parasitological prevalence and intensity of infections [1]. However, it is well known that the current conventional mapping design for schistosomiasis has shown several limitations and may lead to several uncertainties and misclassification of some districts and their eligibility for PC. These inaccuracies prevent successful PC coverage of all populations that need treatment and, therefore, jeopardise the achievement of schistosomiasis elimination [2]. Our recent studies have revealed that precision mapping of schistosomiasis is an essential requirement to move from disease control toward interruption of schistosome transmission in sub-Saharan Africa. As schistosomiasis is a focal disease geographically, having a high-resolution map is necessary if current or future interventions are to be targeted accordingly. Precision mapping is defined as conducting sampling at a much finer geographical resolution, potentially examining all schools within every subunit in each implementation unit in order to eliminate the errors caused by missing the focal variation in schistosomiasis prevalence. Indeed, current mapping protocols and sampling frames perform badly when assessing this landscape

Item Type: Article
Subjects: QV Pharmacology > Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > QV 253 Anthelmintics
WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 810 Schistosomiasis
Faculty: Department: Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):
SWORD Depositor: JISC Pubrouter
Depositing User: Stacy Murtagh
Date Deposited: 14 Aug 2018 16:10
Last Modified: 02 Dec 2019 12:53


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