Items where LSTM Author is "Davies, Jill"

Article

Storm, Janet ORCID: https://orcid.org/0000-0001-7812-4220, Wu, Yang, Davies, Jill, Moxon, Christopher A. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2020) 'Testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function'. Wellcome Open Research, Vol 5, Issue 34.

Hong, David, Leung, S, Amporndanai, Kangsa, Davies, Jill, Priestley, Richard, Nixon, Gemma L., Berry, Neil G., Samar Hasnain, S., Antonyuk, Svetlana, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O’Neill, Paul M. (2018) 'Potent Antimalarial 2-Pyrazolyl Quinolone bc1 (Qi) Inhibitors with Improved Drug-like Properties'. ACS Medicinal Chemistry Letters, Vol 9, Issue 12, pp. 1205-1210.

O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Díaz, Jiménez, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A, Ryan, Eileen, Chen, Gong, Shackleford, David M, Davies, Jill, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.'. Bioorganic and Medicinal Chemistry, Vol 26, Issue 11, pp. 2996-3005.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.'. Scientific Reports, Vol 8, Issue 1, p. 1384.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Priestley, Richard, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Davies, Jill, Waterhouse, David, Cook, Darren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis'. Proceedings of the National Academy of Sciences of the United States of America, Vol 114, Issue 45, E9712-E9721.

O'Neill, Paul M, Amewu, Richard K, Charman, Susan A, Sabbani, Sunil, Gnädig, Nina F, Straimer, Judith, Fidock, David A, Shore, Emma R, Roberts, Natalie L, Wong, Michael H-L, Hong, W David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M, Campbell, Simon, Smith, Dennis A, Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N, Marfurt, Jutta, Palmer, Michael J, Copple, Ian M, Mercer, Amy E, Ruecker, Andrea, Delves, Michael J, Sinden, Robert E, Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H M, Zeeman, Anne-Marie, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.'. Nature Communications, Vol 8, e15159.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Jo, Metugene, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Short Course, High Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis'. Scientific Reports, Vol 7, Issue 210.

Stanton, Michelle ORCID: https://orcid.org/0000-0002-1754-4894, Adriko, M, Arinaitwe, M, Howell, Alison, Davies, Juliet, Allison, Gillian, LaCourse, James ORCID: https://orcid.org/0000-0001-9261-7136, Muheki, E, Kabatereine, N and Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420 (2017) 'Intestinal schistosomiasis in Uganda at high altitude (>1400 m): malacological and epidemiological surveys on Mount Elgon and in Fort Portal crater lakes reveal extra preventive chemotherapy needs'. Infectious Diseases of Poverty, Vol 6, Issue 1, p. 34.

Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Guimaraes, Ana, Davies, Jill, Waterhouse, David, Cook, Darren, Myhill, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2016) 'Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis'. Scientific Reports, Vol 6, p. 23458.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Shone, Alison, Mubaraki, Murad A., Srivastava, Abhishek, Hill, Alasdair, Antoine, Thomas, Warman, Ashley, Davies, Jill, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet C, Sharma, Raman, Gibbons, Peter, Hong, David W, Pacorel, Bénédicte, Lawrenson, Alexandre S, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Stocks, Paul A., Nixon, Gemma, Chadwick, James, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Delves, Michael J, Sinden, Robert E, Zeeman, Anne-Marie, Kocken, Clemens H M, Berry, Neil G, O'Neill, Paul M and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2012) 'Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 109, Issue 21, pp. 8298-303.

Gordey, Erin E, Yadav, Paras N, Merrin, Marcus P, Davies, Jill, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Woodman, Grant M J, Sadowy, Amber L, Smith, Todd G and Gossage, Robert A (2011) 'Synthesis and biological activities of 4-N-(anilinyl-n-[oxazolyl])-7-chloroquinolines (n=3' or 4') against Plasmodium falciparum in in vitro models.'. Bioorganic & Medicinal Chemistry Letters, Vol 21, Issue 15, pp. 4512-5.

O'Neill, Paul M, Amewu, Richard K, Nixon, Gemma L, Bousejra ElGarah, Fatima, Mungthin, Mathirut, Chadwick, James, Shone, Alison, Vivas, Livia, Lander, Hollie, Barton, Victoria, Muangnoicharoen, Sant, Bray, Patrick, Davies, Jill, Park, B Kevin, Wittlin, Sergio, Brun, Reto, Preschel, Michael, Zhang, Kesheng and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2010) 'Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.'. Angewandte Chemie (International ed. in English), Vol 49, Issue 33, pp. 5693-7.

Amewu, Richard, Gibbons, Peter, Mukhtar, Amira, Stachulski, Andrew V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hall, Charlotte, Rimmer, Karen, Davies, Jill, Vivas, Livia, Bacsa, John, Mercer, Amy E., Nixon, Gemma, Stocks, Paul A. and O'Neill, Paul M. (2010) 'Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.'. Organic & biomolecular chemistry, Vol 8, Issue 9, pp. 2068-77.

O'Neill, Paul M., Shone, Alison, Stanford, Deborah, Nixon, Gemma, Asadollahy, Eghbaleh, Park, B. Kevin, Maggs, James L., Roberts, Phil, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Davies, Jill, Berry, Neil, Hall, Charlotte, Rimmer, Karen, Winstanley, Peter A., Hindley, Stephen, Bambal, Ramesh B., Davis, Charles B., Bates, Martin, Gresham, Stephanie L., Brigandi, Richard A., Gomez-de-las-Heras, Federico M., Gargallo, Domingo V., Parapini, Silvia, Vivas, Livia, Lander, Hollie, Taramelli, Donatella and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine'. Journal of Medicinal Chemistry, Vol 52, Issue 7, pp. 1828-1844.

Jones, M., Mercer, A. E., Stocks, Paul A., La Pensee, L. J. I., Cosstick, R., Park, B. K., Kennedy, M. E., Piantanida, I., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Bray, Patrick, Rawe, S. L., Baird, J., Charidza, T., Janneh, O. and O'Neill, P. M. (2009) 'Antitumour and antimalarial activity of artemisinin-acridine hybrids'. Bioorganic & Medicinal Chemistry Letters, Vol 19, Issue 7, pp. 2033-2037.

Araujo, N. C. P., Barton, V., Jones, M., Stocks, Paul A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Bray, Patrick, Shone, Alison, Cristiano, M. L. S. and O'Neill, P. M. (2009) 'Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates'. Bioorganic & Medicinal Chemistry Letters, Vol 19, Issue 7, pp. 2038-2043.

Sabbani, S., Stocks, Paul A., Ellis, G. L., Davies, Jill, Hedenstrom, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Piperidine dispiro-1,2,4-trioxane analogues'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 21, pp. 5804-5808.

Ellis, G. L., Amewu, R., Sabbani, S., Stocks, Paul A., Shone, Alison, Stanford, D., Gibbons, P., Davies, Jill, Vivas, L., Charnaud, S., Bongard, E., Hall, Charlotte, Rimmer, Karen, Lozanom, S., Jesus, M., Gargallo, D., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles'. Journal of Medicinal Chemistry, Vol 51, Issue 7, pp. 2170-2177.

Stocks, Paul A., Bray, Patrick, Barton, V. E., Al-Helal, Mohammed, Jones, M., Araujo, N. C., Gibbons, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hughes, Ruth, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Davies, Jill, Amewu, R., Mercer, A. E., Ellis, G. and O'Neill, P. M. (2007) 'Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs'. Angewandte Chemie-International Edition, Vol 46, Issue 33, pp. 6278-6283.

Amewu, R., Stachulski, A. V., Berry, N. G., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Labat, G., Rossignol, J. F. and O'Neill, P. M. (2006) 'Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 23, pp. 6124-6130.

Amewu, R., Stachulski, A. V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Berry, N. G., Bray, Patrick, Davies, Jill, Labat, G., Vivas, L. and O'Neill, P. M. (2006) 'Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin'. Organic & Biomolecular Chemistry, Vol 4, Issue 24, pp. 4431-4436.

O'Neill, P. M., Verissimo, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill, Korshin, E. E., Araujo, N., Pugh, M. D., Cristiano, M. L. S., Stocks, Paul A. and Bachi, M. D. (2006) 'Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore'. Bioorganic & Medicinal Chemistry Letters, Vol 16, Issue 11, pp. 2991-2995.

O'Neill, P. M., Rawe, S. L., Borstnik, K., Miller, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bray, Patrick, Davies, Jill, Oh, C. H. and Posner, G. H. (2005) 'Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: Implications for the molecular mechanism of action of the artemisinins'. Chembiochem, Vol 6, Issue 11, pp. 2048-2054.

O'Neill, P. M., Mukhtar, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bickley, J. F., Davies, Jill, Bachi, M. D. and Stocks, Paul A. (2004) 'Application of thiol-olefin co-oxygenation methodology to a new synthesis of the 1,2,4-trioxane pharmacophore [Letter]'. Organic Letters, Vol 6, Issue 18, pp. 3035-3038.

Jeyadevan, J. P., Bray, Patrick, Chadwick, J., Mercer, A. E., Byrne, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Park, B. K., Williams, D. P., Cosstick, R., Davies, Jill, Higson, A. P., Irving, E., Posner, G. H. and O'Neill, P. M. (2004) 'Antimalarial and Antitumor Evaluation of Novel C-10 Non-Acetal Dimers of 10β-(2-Hydroxyethyl)deoxoartemisinin'. Journal of Medicinal Chemistry, Vol 47, Issue 5, pp. 1290-1298.

O'Neill, Paul M., Hindley, Stephen, Pugh, Matthew D., Davies, Jill, Bray, Patrick, Park, B. Kevin, Kapu, Dauda S., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Stocks, Paul A. (2003) 'Co(thd)(2): a superior catalyst for aerobic epoxidation and hydroperoxysilylation of unactivated alkenes: application to the synthesis of spiro-1,2,4-trioxanes'. Tetrahedron Letters, Vol 44, Issue 44, pp. 8135-8138.

Bray, Patrick, Saliba, K. J., Davies, Jill, Spiller, D. G., White, M. R. H., Kirk, K. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2002) 'Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH'. Molecular and Biochemical Parasitology, Vol 119, Issue 2, pp. 301-304.

Bray, Patrick, Saliba, K. J., Davies, Jill, Spiller, D. G., White, M. R. H., Kirk, K. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2002) 'Further comments on the distribution of acridine orange fluorescence in P-falciparum-infected erythrocytes'. Molecular and Biochemical Parasitology, Vol 119, Issue 2, pp. 311-313.

O'Neill, P. M., Pugh, M., Stachulski, A. V., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davies, Jill and Park, B. K. (2001) 'Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin: synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues'. Journal of the Chemical Society-Perkin Transactions 1, Issue 20, pp. 2682-2689.

O'Neill, P. M., Pugh, M., Davies, Jill, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Park, B. K. (2001) 'Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-en-1-ols: application to a new synthesis of 1,2,4-trioxanes'. Tetrahedron Letters, Vol 42, Issue 27, pp. 4569-4571.