Items where LSTM Author is "Crittenden, Edouard"

Article

Vázquez Torres, Susana, Benard Valle, Melisa, Mackessy, Stephen P., Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Ahmadi, Shirin, Burlet, Nick J., Muratspahić, Edin, Sappington, Isaac, Overath, Max D., Rivera-de-Torre, Esperanza, Ledergerber, Jann, Laustsen, Andreas H., Boddum, Kim, Bera, Asim K., Kang, Alex, Brackenbrough, Evans, Cardoso, Iara, Crittenden, Edouard, Edge, Rebecca J., Decarreau, Justin, Ragotte, Robert J., Pillai, Arvind S., Abedi, Mohamad, Han, Hannah L., Gerben, Stacey R., Murray, Analisa, Skotheim, Rebecca, Stuart, Lynda, Stewart, Lance, Fryer, Thomas J. A., Jenkins, Timothy P. and Baker, David (2025) 'De novo designed proteins neutralize lethal snake venom toxins'. Nature. (In Press)

Murray, Shea, Cunningham, Lucas, Rowley, Paul, Crittenden, Edouard, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, LaCourse, James ORCID: https://orcid.org/0000-0001-9261-7136, Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420 and Juhász, Alexandra (2025) 'A preliminary microscopic and molecular epidemiological survey of endoparasites within wild-caught and UK captive-bred reptiles: Assessing a potential parasitic disease public health risk?'. International Journal for Parasitology: Parasites and Wildlife, Vol 26, p. 101039. (In Press)

Bartlett, Keirah, Hall, Steven, Rasmussen, Sean A., Crittenden, Edouard, Dawson, Charlotte, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Laprade, William, Harrison, Robert, Saviola, Anthony J., Modahl, Cassandra, Jenkins, Timothy P., Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Gutiérrez, José María and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib'. Proceedings of the National Academy of Sciences of the United States of America, Vol 121, Issue 19, e2315597121.

Hall, Steven, Rasmussen, Sean A., Crittenden, Edouard, Dawson, Charlotte, Bartlett, Keirah, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Kool, Jeroen, Gutiérrez, José María and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2023) 'Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms'. Nature Communications, Vol 14, Issue 1, e7812.

Laprade, William, Bartlett, Keirah, Christensen, Charlotte R., Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Patel, Rohit, Crittenden, Edouard, Dawson, Charlotte, Mansourvar, Marjan, Wolff, Darian S., Fryer, Thomas, Laustsen, Andreas H., Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Gutiérrez, José María, Hall, Steven and Jenkins, Timothy P. (2023) 'Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL'. Scientific Reports, Vol 13, Issue 1, e21662.

Ahmadi, Shirin, Pachis, Spyridon T., Kalogeropoulos, Konstantinos, McGeoghan, Farrell, Canbay, Vahap, Hall, Steven, Crittenden, Edouard, Dawson, Charlotte, Bartlett, Keirah, Gutiérrez, José María, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Keller, Ulrich auf dem and Laustsen, Andreas H. (2022) 'Proteomics and histological assessment of an organotypic model of human skin following exposure to Naja nigricollis venom'. Toxicon, Vol 220, p. 106955.

Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Litschka-Koen, Thea, Edge, Becky, Al Solaiss, Jaffer, Crittenden, Edouard, Hall, Steven, Westhorpe, Adam, Thomas, Brent ORCID: https://orcid.org/0000-0003-1118-5429, Murray, James, Shongwe, Nondusimo, Padidar, Sara, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Pons, Jonathan and Harrison, Robert (2022) 'Two snakebite antivenoms have potential to reduce Eswatini’s dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing'. PLoS Neglected Tropical Diseases, Vol 16, Issue 9, e0010496.

Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Dawson, Charlotte, Crittenden, Edouard, Edge, Becky, Hall, Steven, Al Solaiss, Jaffer, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Harrison, Robert and Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482 (2022) 'Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition'. Scientific Reports, Vol 12, Issue 1, p. 11328.

Alomran, Nessrin ORCID: https://orcid.org/0000-0002-9916-8182, Blundell, Pat ORCID: https://orcid.org/0000-0003-3386-5660, Al Solaiss, Jaffer, Crittenden, Edouard, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Dawson, Charlotte, Edge, Becky, Hall, Steven, Harrison, Robert, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296 and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2022) 'Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms.'. Toxins, Vol 14, Issue 7, p. 443.

Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Xie, Chunfang, Westhorpe, Adam, Hall, Steven, Edge, Becky, Al Solaiss, Jaffer, Crittenden, Edouard, Marriott, Amy, Harrison, Robert, Kool, Jeroen and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2022) 'In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus'. Toxicon, Vol 14, p. 100118.

Alomran, Nessrin ORCID: https://orcid.org/0000-0002-9916-8182, Al Solaiss, Jaffer, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Crittenden, Edouard, Harrison, Robert, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482 and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2021) 'Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro crossreactivity and in vivo neutralisation of geographically diverse snake venoms'. PLoS Neglected Tropical Diseases, Vol 15, Issue 8, e0009659.

Avella, Ignazio, Barajas-Ledesma, Edgar, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Harrison, Robert, Rowley, Paul, Crittenden, Edouard, Wüster, Wolfgang, Castiglia, Riccardo, Holland, Chris and van der Meijden, Arie (2021) 'Unexpected lack of specialisation in the flow properties of spitting cobra venom'. The Journal of Experimental Biology, Vol 224, jeb229229.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Xie, C, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Al Solaiss, Jaffer, Crittenden, Edouard, Dawson, Charlotte, Softley, R, Bartlett, Keirah, Harrison, Robert, Kool, J and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite'. Nature communications, Vol 11, Issue 6094.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Hales, MS, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Al Solaiss, Jaffer, Crittenden, Edouard, Calvete, Juan, Evans, Chloe, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Harrison, Robert, Kool, Jeroen and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'Preclinical validation of a repurposed metal chelator as an early intervention therapeutic for hemotoxic snakebite'. Science Translational Medicine, Vol 12, Issue 542, eaay8314.

Conference or Workshop Item

Hall, Steven, Crittenden, Edouard, Dawson, Charlotte, Bartlett, Keirah, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217 and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2023) 'Drug combination therapies effectively inhibit the dermonecrotic activity of cytotoxic venoms from geographically diverse snake species in vivo' in British Pharmacological Society 2022, Tuesday 13th September.

Data Collection

Laprade, William, Bartlett, Keirah, Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Patel, Rohit, Crittenden, Edouard, Dawson, Charlotte, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Hall, Steven (2023) Dataset for the article: Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL. [Data Collection]