Items where LSTM Author is "Cook, Darren"

Article

Quek, Shannon ORCID: https://orcid.org/0000-0002-1583-9541, Cook, Darren, Wu, Yang, Marriott, Amy, Steven, Andrew, Johnston, Kelly, Ford, Louise, Archer, John, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2022) 'Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment'. Proceedings of the National Academy of Sciences, Vol 119, Issue 15, e2120003119.

Mattick, John, Libro, Silvia, Bromley, Robin, Chaicumpa, Wanpen, Chung, Matthew, Cook, Darren, Khan, Mohammad Behram, Kumar, Nikhil, Lau, Yee-Ling, Misra-Bhattacharya, Shailja, Rao, Ramakrishna, Sadzewicz, Lisa, Saeung, Atiporn, Shahab, Mohd, Sparklin, Benjamin C., Steven, Andrew, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Tallon, Luke J., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Moorhead, Andrew R, Michalski, Michelle, Foster, Jeremy M. and Dunning Hotopp, Julie C. (2021) 'X-treme loss of sequence diversity linked to neo-X chromosomes in filarial nematodes'. PLoS Neglected Tropical Diseases, Vol 15, Issue 10, e0009838.

McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hong, David and O’Neill, Paul M. (2021) 'Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis'. ACS Medicinal Chemistry Letters, Vol 12, Issue 9, pp. 1421-1426.

Pilotte, Nils, Cook, Darren, Pryce, Joseph, Zulch, Michael F, Minetti, Corrado ORCID: https://orcid.org/0000-0001-7862-4874, Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981 and Williams, Steven A (2019) 'Laboratory evaluation of molecular xenomonitoring using mosquito excreta/feces to amplify Plasmodium, Brugia, and Trypanosoma DNA'. Gates Open Research, Vol 3, Issue 1734.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, von Geldern, Thomas W, Ford, Louise, Hübner, Marc P, Marsh, Kennan, Johnston, Kelly, Sjoberg, Hanna, Specht, Sabine, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Tyrer, Hayley, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Steven, Andrew, Archer, John, Bloemker, Dominique, Lenz, Franziska, Koschel, Marianne, Ehrens, Alexandra, Metuge, Haelly M, Chunda, Valerinne C, Ndongmo Chounna, Patrick W, Njouendou, Abdel J, Fombad, Fanny F, Carr, Robert, Morton, Howard E, Aljayyoussi, Ghaith, Hoerauf, Achim, Wanji, Samuel, Kempf, Dale J, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis'. Science Translational Medicine, Vol 11, Issue 483.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Bardelle, Catherine, Harper, Paul, Hong, Weiqian, Borjesson, Ulf, Johnston, Kelly, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Cook, Darren, Steven, Andrew, Archer, John, McGillan, Paul, Charoensutthivarakul, Sitthivut, Bibby, Jaclyn, Sharma, Raman, Nixon, Gemma, Slatko, Barton, Cantin, Lindsey, Wu, Bo, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ford, Louise, Rich, Kirsty, Wigglesworth, Mark, Berry, Neil, O'Neill, Paul, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides'. Nature Communications, Vol 10, Issue 11.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Furlong-Silva, Julio, Sjoberg, Hanna, Cross, Stephen, Halliday, Alice, Guimaraes, Ana, Cook, Darren, Steven, Andrew, Van Rooijen, Nico, Allen, Judith, Jenkins, Stephen and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2018) 'Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia'. PLoS Pathogens, Vol 14, Issue 3, e1006949.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.'. Scientific Reports, Vol 8, Issue 1, p. 1384.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Priestley, Richard, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Davies, Jill, Waterhouse, David, Cook, Darren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis'. Proceedings of the National Academy of Sciences of the United States of America, Vol 114, Issue 45, E9712-E9721.

Cook, Darren, Pilotte, Nils, Minetti, Corrado ORCID: https://orcid.org/0000-0001-7862-4874, Williams, Steven A. and Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981 (2017) 'A superhydrophobic cone to facilitate the xenomonitoring of filarial parasites, malaria, and trypanosomes using mosquito excreta/feces'. Gates Open Research, Vol 1, p. 7.

Johnston, Kelly, Cook, Darren, Berry, Neil, Hong, Weiqian David, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Goddard, Megan, Ford, Louise, Nixon, Gemma, O'Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library'. Science Advances, Vol 3, Issue 9, eaao1551.

Schroeder, Jan-Hendrik, McCarthy, David, Szestak, Tadge, Cook, Darren, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Lawson, Charlotte and Lawrence, Rachel (2017) 'Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner'. PLoS Neglected Tropical Diseases, Vol 11, Issue 5, e0005592.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Jo, Metugene, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Short Course, High Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis'. Scientific Reports, Vol 7, Issue 210.

Gleave, Katherine, Cook, Darren, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981 (2016) 'Filarial infection influences mosquito behaviour and fecundity'. Scientific Reports, Vol 6, Issue 36319.

Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Guimaraes, Ana, Davies, Jill, Waterhouse, David, Cook, Darren, Myhill, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2016) 'Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis'. Scientific Reports, Vol 6, p. 23458.

Halliday, Alice, Guimaraes, Ana, Tyrer, Hayley, Metuge, Haelly, Patrick, Chounna, Arnaud, Kengne-Ouafo, Kwenti, Tayong, Forsbrook, George, Steven, Andrew, Cook, Darren, Enyong, Peter, Wanji, Samuel, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 (2014) 'A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis'. Parasites & Vectors, Vol 7, e472.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Development and Validation of a High-Throughput Anti-Wolbachia Whole-Cell Screen: A Route to Macrofilaricidal Drugs against Onchocerciasis and Lymphatic Filariasis'. Journal of Biomolecular Screening, Vol 20, Issue 1, pp. 64-69.

Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Wuster, W., Cook, Darren, Bolton, Fiona, King, Sarah, Pla, D., Sanz, L., Calvete, J. J. and Harrison, Robert (2014) 'Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms'. Proceedings of the National Academy of Sciences, Vol 111, Issue 25, pp. 9205-9210.

Voronin, Denis, Cook, Darren, Steven, Andrew and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2012) 'Autophagy regulates Wolbachia populations across diverse symbiotic associations.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 109, Issue 25, E1638-E1646.

Harrison, Robert, Cook, Darren, Renjifo, Camila, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Currier, Rachel B. and Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537 (2011) 'Research strategies to improve snakebite treatment: challenges and progress.'. Journal of Proteomics, Vol 74, Issue 9, pp. 1768-1780.

Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Cook, Darren, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Nasidi, Abdulsalami, Durfa, Nandul, Wüster, Wolfgang and Harrison, Robert (2010) 'Pre-clinical assays predict pan-African Echis viper efficacy for a species-specific antivenom.'. PLoS Neglected Tropical Diseases, Vol 4, Issue 10, e851.

Cook, Darren, Samarasekara, Chamali L, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Kinne, Joerg, Wernery, Ulrich and Harrison, Robert (2010) 'Analysis of camelid IgG for antivenom development: Immunoreactivity and preclinical neutralisation of venom-induced pathology by IgG subclasses, and the effect of heat treatment.'. Toxicon, Vol 56, Issue 4, pp. 596-603.

Cook, Darren, Owen, Timothy, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Kinne, Joerg, Wernery, Ulrich and Harrison, Robert (2010) 'Analysis of camelid IgG for antivenom development: Serological responses of venom-immunised camels to prepare either monospecific or polyspecific antivenoms for West Africa.'. Toxicon, Vol 56, Issue 3, pp. 363-72.

Cook, Darren, Owen, Timothy, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Kinne, Joerg, Wernery, Ulrich and Harrison, Robert (2010) 'Analysis of camelid antibodies for antivenom development: Neutralisation of venom-induced pathology.'. Toxicon, Vol 56, Issue 3, pp. 373-80.

Conference or Workshop Item

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Halliday, Alice, Guimaraes, Ana, Steven, Andrew, van Rooijen, N., Else, K., Cook, Darren and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2013) 'M2a macrophages are necessary and sufficient to mediate eosinophil-dependent immunity to filarial helminth infection' in Annual Congress of the British Society for Immunology, Liverpool, 2-5 December 2013.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Guimaraes, Ana, Steven, Andrew, Cook, Darren, van Rooijen, N. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2012) 'Co-operation between innate CCR3-expressing granulocytes and macrophages in controlling early establishment of Brugia malayi infection' in European Congress of Immunology, Glasgow, 5-8 September 2012.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Guimaraes, Ana, Steven, Andrew, Cook, Darren and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2012) 'Development of murine pathology models to test interventions against filarial lymphoedema reveals a therapeutic role of VEGFR3 ligation' in European Congress of Immunology, Glasgow, 5-8 September 2012.