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Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Ardrey, Alison, Hafiz, Taghreed, Dyer, Lauri-Anne, Warman, Ashley, Mosallam, Nada, Nixon, Gemma, Fisher, Nicholas, Hong, W. David, Leung, Suet C., Aljayyoussi, Ghaith, Bibby, Jaclyn, Almeida, Deepak V., Converse, Paul J., Fotouhi, Nader, Berry, Neil G., Nuermberger, Eric L., Upton, Anna M., O’Neill, Paul M., Ward, Steve
ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595
(2023)
'Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis'. ACS Infectious Diseases, Vol 9, Issue 2, pp. 221-238.
Hong, David, Gibbons, Peter, Leung, Suet C, Amewu, Richard, Stocks, Paul A, Stachulski, Andrew, Horta, Pedro, Cristiano, Maria L. S., Shone, Alison, Moss, Darren, Ardrey, Alison, Sharma, Raman, Warman, Ashley, Bedingfield, Paul, Fisher, Nicholas, Aljayyoussi, Ghaith, Mead, Sally, Caws, Maxine ORCID: https://orcid.org/0000-0002-9109-350X, Berry, Neil, Ward, Steve
ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595, O’Neill, Paul M and Nixon, Gemma L
(2017)
'Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis'. Journal of Medicinal Chemistry, Vol 60, Issue 9, pp. 3703-3726.
Warman, Ashley, Rito, Teresa S, Fisher, Nicholas, Moss, Darren M., Berry, Neil G, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595
(2013)
'Antitubercular pharmacodynamics of phenothiazines'. Journal of Antimicrobial Chemotherapy, Vol 68, Issue 4, pp. 869-880.
Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Shone, Alison, Mubaraki, Murad A., Srivastava, Abhishek, Hill, Alasdair, Antoine, Thomas, Warman, Ashley, Davies, Jill, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet C, Sharma, Raman, Gibbons, Peter, Hong, David W, Pacorel, Bénédicte, Lawrenson, Alexandre S, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Stocks, Paul A., Nixon, Gemma, Chadwick, James, Hemingway, Janet
ORCID: https://orcid.org/0000-0002-3200-7173, Delves, Michael J, Sinden, Robert E, Zeeman, Anne-Marie, Kocken, Clemens H M, Berry, Neil G, O'Neill, Paul M and Ward, Stephen
ORCID: https://orcid.org/0000-0003-2331-3192
(2012)
'Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 109, Issue 21, pp. 8298-303.
Sharma, Raman, Lawrenson, Alexandre S, Fisher, Nicholas, Warman, Ashley, Shone, Alison, Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet, Gibbons, Peter, Hong, David W, Stocks, Paul A., Nixon, Gemma L, Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595 and Berry, Neil G
(2012)
'Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.'. Journal of medicinal chemistry, Vol 55, Issue 7, pp. 3144-54.
Fisher, Nicholas, Abd Majid, Roslaini, Antoine, Thomas, Al-Helal, Mohammed, Warman, Ashley, Johnson, David, Lawrenson, Alexandre S., Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, O'Neill, Paul M, Ward, Stephen
ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595
(2012)
'Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.'. The Journal of Biological Chemistry, Vol 287, Issue 13, pp. 9731-9741.
Pidathala, Chandrakala, Amewu, Richard, Pacorel, Bénédicte, Nixon, Gemma L, Gibbons, Peter, Hong, W David, Leung, Suet C, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen
ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M
(2012)
'Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1831-1843.
Leung, Suet C, Gibbons, Peter, Amewu, Richard, Nixon, Gemma L, Pidathala, Chandrakala, Hong, W David, Pacorel, Bénédicte, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen
ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M
(2012)
'Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1844-1857.
Kongkathip, Ngampong, Pradidphol, Narathip, Hasitapan, Komkrit, Grigg, Ronald, Kao, Wei-Chun, Hunte, Carola, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Kongsaeree, Palangpon, Chuawong, Pitak and Kongkathip, Boonsong
(2010)
'Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents.'. Journal of medicinal chemistry, Vol 53, Issue 3, pp. 1211-1221.
Book Section
Fisher, Nicholas, Warman, Ashley, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo
ORCID: https://orcid.org/0000-0001-6356-6595
(2010)
'Chapter 17 Type II NADH: Quinone Oxidoreductases of Plasmodium Falciparum and Mycobacterium Tuberculosis. Kinetic and High-Throughput Assays' in:
Allison, W. S. and Scheffler, I. E., (eds)
Methods in Enzymology, 456, San Diego, Calif., Academic Press, pp. 303-320.