Items where LSTM Author is "Ford, Louise"

Article

Hoffmann, Guillaume, Lukarska, Maria, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Masters, Ellen, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Jensen, Malene Ringkjøbing and Palencia, Andrés (2024) 'Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.'. Science Advances, Vol 10, Issue 28, eado1453.

Quek, Shannon ORCID: https://orcid.org/0000-0002-1583-9541, Cook, Darren, Wu, Yang, Marriott, Amy, Steven, Andrew, Johnston, Kelly, Ford, Louise, Archer, John, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2022) 'Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment'. Proceedings of the National Academy of Sciences, Vol 119, Issue 15, e2120003119.

McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hong, David and O’Neill, Paul M. (2021) 'Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis'. ACS Medicinal Chemistry Letters, Vol 12, Issue 9, pp. 1421-1426.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Clark, Roger, Bardelle, Catherine, Harper, Paul, Collier, Matthew, Johnston, Kelly, Plant, Helen, Plant, Darren, McCall, Eileen, Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Ford, Louise, Murray, David, Rich, Kirsty, Wigglesworth, Mark, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership'. SLAS Discovery, Vol 24, Issue 5, pp. 537-547.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, von Geldern, Thomas W, Ford, Louise, Hübner, Marc P, Marsh, Kennan, Johnston, Kelly, Sjoberg, Hanna, Specht, Sabine, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Tyrer, Hayley, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Steven, Andrew, Archer, John, Bloemker, Dominique, Lenz, Franziska, Koschel, Marianne, Ehrens, Alexandra, Metuge, Haelly M, Chunda, Valerinne C, Ndongmo Chounna, Patrick W, Njouendou, Abdel J, Fombad, Fanny F, Carr, Robert, Morton, Howard E, Aljayyoussi, Ghaith, Hoerauf, Achim, Wanji, Samuel, Kempf, Dale J, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis'. Science Translational Medicine, Vol 11, Issue 483.

von Geldern, Thomas W, Morton, Howard E, Clark, Rick F, Brown, Brian S, Johnston, Kelly, Ford, Louise, Specht, Sabine, Carr, Robert A, Stolarik, Deanne F, Ma, Junli, Rieser, Matthew J, Struever, Dominique, Frohberger, Stefan J, Koschel, Marianne, Ehrens, Alexandra, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Hübner, Marc P, Hoerauf, Achim, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kennan and Kempf, Dale J (2019) 'Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.'. PLoS Neglected Tropical Diseases, Vol 13, Issue 2, e0007159.

Jacobs, Robert Toms, Lunde, Christopher S, Freund, Yvonne R, Hernandez, Vincent, Li, Xianfeng, Xia, Yi, Carter, David S, Berry, Pamela, Halladay, Jason, Rock, Fernando, Stefanakis, Rianna, Easom, Eric E, Plattner, Jacob J, Ford, Louise, Johnston, Kelly L, Cook, Darren A N, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Myhill, Laura, Tyrer, Hayley, Gamble, Joanne, Guimaraes, Ana F, Steven, Andrew, Lenz, Franziska, Ehrens, Alexandra, Frohberger, Stefan J, Koschel, Marianne, Hoerauf, Achim, Hübner, Marc P, McNamara, Case, Bakowski, Malina A, Turner, Joseph D ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark J ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Stephen A ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.'. Journal of medicinal chemistry.

Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Cook, Darren A N, Siu, Amy, Shiotani, Motohiro, Webborn, Peter J H, Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J, Ehrens, Alexandra, Hübner, Marc P, Hoerauf, Achim, Roberts, Adam ORCID: https://orcid.org/0000-0002-0760-3088, Hubbard, Alasdair ORCID: https://orcid.org/0000-0001-6668-9179, Tate, Edward W, Serwa, Remigiusz A, Leung, Suet C, Qie, Li, Berry, Neil G, Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2019) 'AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 116, Issue 4, pp. 1414-1419.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Bardelle, Catherine, Harper, Paul, Hong, Weiqian, Borjesson, Ulf, Johnston, Kelly, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Cook, Darren, Steven, Andrew, Archer, John, McGillan, Paul, Charoensutthivarakul, Sitthivut, Bibby, Jaclyn, Sharma, Raman, Nixon, Gemma, Slatko, Barton, Cantin, Lindsey, Wu, Bo, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ford, Louise, Rich, Kirsty, Wigglesworth, Mark, Berry, Neil, O'Neill, Paul, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides'. Nature Communications, Vol 10, Issue 11.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.'. Scientific Reports, Vol 8, Issue 1, p. 1384.

Specht, Sabine, Pfarr, Kenneth M, Arriens, Sandra, Hübner, Marc P, Klarmann-Schulz, Ute, Koschel, Marianne, Sternberg, Sonja, Martin, Coralie, Ford, Louise, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Hoerauf, Achim (2018) 'Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model.'. PLoS Neglected Tropical Diseases, Vol 12, Issue 1, e0006116.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Priestley, Richard, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Davies, Jill, Waterhouse, David, Cook, Darren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis'. Proceedings of the National Academy of Sciences of the United States of America, Vol 114, Issue 45, E9712-E9721.

Johnston, Kelly, Cook, Darren, Berry, Neil, Hong, Weiqian David, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Goddard, Megan, Ford, Louise, Nixon, Gemma, O'Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library'. Science Advances, Vol 3, Issue 9, eaao1551.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Jo, Metugene, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Short Course, High Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis'. Scientific Reports, Vol 7, Issue 210.

Klarmann-Schulz, Ute, Specht, Sabine, Debrah, Alexander Yaw, Batsa, Linda, Ayisi-Boateng, Nana Kwame, Osei-Mensah, Jubin, Mubarik, Yusif, Konadu, Peter, Ricchiuto, Arcangelo, Fimmers, Rolf, Arriens, Sandra, Dubben, Bettina, Ford, Louise, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Hoerauf, Achim (2017) 'Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial'. PLoS Neglected Tropical Diseases, Vol 11, Issue 1, e0005156.

Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Guimaraes, Ana, Davies, Jill, Waterhouse, David, Cook, Darren, Myhill, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2016) 'Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis'. Scientific Reports, Vol 6, p. 23458.

Reimer, Lisa ORCID: https://orcid.org/0000-0002-9711-4981, Adams, Emily ORCID: https://orcid.org/0000-0002-0816-2835, Paine, Mark ORCID: https://orcid.org/0000-0003-2061-7713, Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, Coleman, Marlize, Thomsen, Edward ORCID: https://orcid.org/0000-0003-1136-6430, MacPherson, Eleanor ORCID: https://orcid.org/0000-0002-7142-1158, Hollingsworth, T, Kelly-Hope, Louise ORCID: https://orcid.org/0000-0002-3330-7629, Bockarie, Moses, Ford, Louise, Harrison, Robert, Stothard, Russell ORCID: https://orcid.org/0000-0002-9370-3420, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hamon, Nicholas and Torr, Steve ORCID: https://orcid.org/0000-0001-9550-4030 (2015) 'Fit for purpose: do we have the right tools to sustain NTD elimination?'. BMC Proceedings, Vol 9, Issue Suppl 10, S5.

Johnston, Kelly, Ford, Louise, Umareddy, Indira, Townson, Simon, Specht, Sabine, Pfarr, Kenneth, Hoerauf, Achim, Altmeyer, Ralf and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis'. International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Issue 3, pp. 278-286.

Voronin, Denis, Guimaraes, Ana, Molyneux, Gemma, Johnston, Kelly, Ford, Louise and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus'. Parasites & Vectors, Vol 7, e462.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Development and Validation of a High-Throughput Anti-Wolbachia Whole-Cell Screen: A Route to Macrofilaricidal Drugs against Onchocerciasis and Lymphatic Filariasis'. Journal of Biomolecular Screening, Vol 20, Issue 1, pp. 64-69.

Foster, Jeremy M, Landmann, Frédéric, Ford, Louise, Johnston, Kelly, Elsasser, Sarah C, Schulte-Hostedde, Albrecht I, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Slatko, Barton E (2014) 'Absence of Wolbachia endobacteria in the human parasitic nematode Dracunculus medinensis and two related Dracunculus species infecting wildlife'. Parasites & Vectors, Vol 7, e140.

Johnston, Kelly, Ford, Louise and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2013) 'Overcoming the Challenges of Drug Discovery for Neglected Tropical Diseases: The AWOL Experience'. Journal of Biomolecular Screening, Vol 19, Issue 3, pp. 335-343.

Wu, Bo, Novelli, Jacopo, Jiang, Daojun, Dailey, Harry A, Landmann, Frédéric, Ford, Louise, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Carlow, Clotilde K S, Kumar, Sanjay, Foster, Jeremy M and Slatko, Barton E (2013) 'Interdomain lateral gene transfer of an essential ferrochelatase gene in human parasitic nematodes.'. Proceedings of the National Academy of Sciences, Vol 110, Issue 19, pp. 7748-7753.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Voronin, Denis, Johnston, Kelly and Ford, Louise (2013) 'Wolbachia filarial interactions.'. Cellular microbiology, Vol 15, Issue 4, pp. 520-26.

Schroeder, Jan-Hendrik, Simbi, Bigboy H, Ford, Louise, Cole, Sara R, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Lawson, Charlotte and Lawrence, Rachel A (2012) 'Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.'. PLoS Neglected Tropical Diseases, Vol 6, Issue 11, e1914.

Johnston, Kelly, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2010) 'Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes'. Parasites & Vectors, Vol 3, e99.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Tendongfor, Nicholas, Esum, Mathias, Johnston, Kelly, Langley, R. Stuart, Ford, Louise, Faragher, Brian, Specht, Sabine, Mand, Sabine, Hoerauf, Achim, Enyong, Peter, Wanji, Samuel and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2010) 'Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.'. PLoS Neglected Tropical Diseases, Vol 4, Issue 4, e660.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Langley, R. Stuart, Johnston, Kelly, Gentil, Katrin, Ford, Louise, Wu, Bo, Graham, Maia, Sharpley, Faye, Slatko, Barton, Pearlman, Eric and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2009) 'Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.'. The Journal of biological chemistry, Vol 284, Issue 33, pp. 22364-22378.

Ford, Louise, Zhang, J., Liu, J., Hashmi, S., Fuhrman, J. A., Oksov, Y. and Lustigman, S. (2009) 'Functional Analysis of the Cathepsin-Like Cysteine Protease Genes in Adult Brugia malayi Using RNA Interference'. PLoS Neglected Tropical Diseases, Vol 3, Issue 2, e377.

Ford, Louise, Johnston, Kelly, Ambrose, P. A., Draper, M. P., Bhatia, B. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'A-Wol Drug Discovery - Screening of Novel Derivatives of Tetracycline with Improved Efficacy over Doxycycline in an in Vitro Wolbachia Cell-Line Assay'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6, p. 128.

Johnston, Kelly, Wu, B., Guimaraes, A., Ford, Louise, Ambrose, Pauline, Slatko, B. E. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'Globomycin: A New Class of Drug with Efficacy against Wolbachia and Filarial Nematodes'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Sup., p. 128.

Foster, J. M., Kumar, S., Ford, Louise, Johnston, Kelly, Ben, R., Graeff-Teixeira, C. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'Absence of Wolbachia endobacteria in the non-filariid nematodes Angiostrongylus cantonensis and A. costaricensis'. Parasites & Vectors, Vol 1, e31.

Saint Andre, A. V., Blackwell, N. M., Hall, L. R., Hoerauf, A., Brattig, N. W., Volkmann, L., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ford, Louise, Hise, A. G., Lass, J. H., Diaconu, E. and Pearlman, E. (2002) 'The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness'. Science, Vol 295, Issue 5561, pp. 1892-1895.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Cross, H. F., Ford, Louise, Makunde, W. H., Prasad, G. B. K. S. and Bilo, K. (2001) 'Wolbachia bacteria in filarial immunity and disease'. Parasite Immunology, Vol 23, Issue 7, pp. 401-409.