Items where Department is "Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group" and Year is 2005

A

Al-Mohammed, H. I., Chance, Michael and Bates, Paul (2005) 'Production and characterization of stable amphotericin-resistant amastigotes and promastigotes of Leishmania mexicana'. Antimicrobial Agents and Chemotherapy, Vol 49, Issue 8, pp. 3274-3280.

B

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O'Neill, P. M., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Current drug development portfolio for antimalarial therapies'. Current Opinion in Pharmacology, Vol 5, Issue 5, pp. 473-478.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2005) 'Malaria parasite transporters as a drug-delivery strategy'. Trends in Parasitology, Vol 21, Issue 7, pp. 299-301.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fidock, D. A., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+ [Letter to the Editor]'. Antimicrobial Agents and Chemotherapy, Vol 49, Issue 11, pp. 4807-4808.

Bray, Patrick, Martin, R. E., Tilley, L., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Kirk, K. and Fidock, D. A. (2005) 'Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance'. Molecular Microbiology, Vol 56, Issue 2, pp. 323-333.

Bray, Patrick, Deed, S., Fox, E., Kalkanidis, M., Mungthin, M., Deady, L. W. and Tilley, L. (2005) 'Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum'. Biochemical Pharmacology, Vol 70, Issue 8, pp. 1158-1166.

Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M (2005) 'Quinolines and artemisinin: Chemistry, biology and history'. Current Topics in Microbiology and Immunology, Vol 295, pp. 3-38.

C

Chaijaroenkul, W., Bangchang, K. N., Mungthin, M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003'. Malaria Journal, Vol 4, p. 37.

Chakravorty, S. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2005) 'The role of ICAM-1 in Plasmodium falciparum cytoadherence'. European Journal of Cell Biology, Vol 84, Issue 1, pp. 15-27.

D

Donnelly, Martin ORCID: https://orcid.org/0000-0001-5218-1497, McCall, Philip ORCID: https://orcid.org/0000-0002-0007-3985, Lengeler, C., Bates, Imelda ORCID: https://orcid.org/0000-0002-0862-8199, D'Alessandro, U., Barnish, Guy, Konradsen, F., Klinkenberg, Eveline, Townson, Harold, Trape, J. F., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Mutero, C. (2005) 'Malaria and urbanization in sub-Saharan Africa'. Malaria Journal, Vol 4.

G

Gallagher, Paul, Bao, Yongde, Serrano, Solange M. T., Laing, Gavin, Theakston, R.David G., Guti, Jos, Escalante, Teresa, Zigrino, Paola, Moura-da-Silva, Ana M., Nischt, Roswitha, Mauch, Cornelia, Moskaluk, Christopher and Fox, Jay W. (2005) 'Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: In vitro and in vivo gene expression analysis of the effects of the toxin'. Archives of Biochemistry and Biophysics, Vol 441, Issue 1, pp. 1-15.

Gitau, Evelyn, Kokwaro, G, Newton, C and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Use of plasma proteomics to discriminate between malaria infected mice from non-infected control mice [MIM-EG-111840]'. Acta Tropica, Vol 95, S46-S47.

Graham, R. L. J., McClean, S., O'Kane, E. J., Theakston, R.David G. and Shaw, C. (2005) 'Adenosine in the venoms from viperinae snakes of the genus Bitis: Identification and quantitation using LC/MS and CE/MS'. Biochemical and Biophysical Research Communications, Vol 333, Issue 1, pp. 88-94.

Gutierrez, J. M., Rojas, E., Quesada, L., Leon, G., Nunez, J., Laing, Gavin, Sasa, M., Renjifo, J. M., Nasidi, A., Warrell, D. A., Theakston, R.David G. and Rojas, G. (2005) 'Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 99, Issue 6, pp. 468-475.

H

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Watkins, W. M. (2005) 'Intensity of malaria transmission and the evolution of drug resistance'. Acta Tropica, Vol 94, Issue 3, pp. 218-229.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Donnelly, Martin ORCID: https://orcid.org/0000-0001-5218-1497 (2005) 'The impact of antimalarial drug resistance mutations on parasite fitness, and its implications for the evolution of resistance'. Drug Resistance Updates, Vol 8, Issue 1-2, pp. 43-50.

Horrocks, P., Pinches, R. A., Chakravorty, S., Papakrivos, J., Christodoulou, Z., Kyes, S. A., Urban, Britta, Ferguson, D. J. P. and Newbold, C. I. (2005) 'PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes'. Journal of Cell Science, Vol 118, Issue 11, pp. 2507-2518.

Howes, J.M., Theakston, R.David G. and Laing, Gavin (2005) 'Antigenic relationships and relative immunogenicities of isolated metalloproteinases from Echis ocellatus venom'. Toxicon, Vol 45, Issue 5, pp. 677-680.

Howes, J.M., Kamiguti, A. S., Theakston, R.David G., Wilkinson, M. C. and Laing, Gavin (2005) 'Effects of three novel metalloproteinases from the venom of the West African saw-scaled viper, Echis ocellatus on blood coagulation and platelets'. Biochimica Et Biophysica Acta-General Subjects, Vol 1724, Issue 1-2, pp. 194-202.

J

Joshi, M. B., Rogers, Matthew E., Shakarian, A. M., Yamage, M., Al-Harthi, S. A., Bates, Paul and Dwyer, D. M. (2005) 'Molecular characterization, expression, and in vivo analysis of LmexCht1'. Journal of Biological Chemistry, Vol 280, Issue 5, pp. 3847-3861.

L

Laing, Gavin, Compton, S. J., Ramachandran, R., Fuller, G. L. J., Wilkinson, M. C., Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Watson, S. P., Kamiguti, A. S., Theakston, R.David G. and Senis, Y. A. (2005) 'Characterization of a novel protein from Proatheris superciliaris venom: Proatherocytin, a 34-kDa platelet receptor PAR1 agonist'. Toxicon, Vol 46, Issue 5, pp. 490-499.

Laing, Gavin and Moura-da-Silva, A. M. (2005) 'Jararhagin and its multiple effects on hemostasis'. Toxicon, Vol 45, Issue 8, pp. 987-996.

Lakshmanan, V., Bray, Patrick, Verdier-Pinard, D., Johnson, David, Horrocks, P., Muhle, R. A., Alakpa, G. E., Hughes, Ruth, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Krogstad, D. J., Sidhu, A. B. S. and Fidock, D. A. (2005) 'A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance'. Embo Journal, Vol 24, Issue 13, pp. 2294-2305.

M

Makanga, M, Bray, Patrick, Horrocks, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria'. Proteomics, Vol 5, Issue 7, pp. 1849-1858.

Mandala, W., Maclennan, C., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Molyneux, Malcolm E (2005) 'Immunological mechanisms determining why some African children develop severe malarial anaemia (SMA) and others cerebral malaria (CM) in response to P-falciparum infection [MIM-WM-392094]'. Acta Tropica, Vol 95, S71-S72.

McGready, R., Stepniewska, K., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Cho, T., Gilveray, G., Looareesuwan, S., White, N. J. and Nosten, F. (2005) 'Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria'. European Journal of Clinical Pharmacology, Vol 62, Issue 5, pp. 367-371.

Muchohi, S. N., Obiero, K., Kokwaro, G. O., Ogutu, B. R., Githiga, I. M., Edwards, Geoffrey and Newton, C. R. J. C. (2005) 'Determination of lorazepam in plasma from children by high-performance liquid chromatography with UV detection'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 824, Issue 1-2, pp. 333-340.

Muchohi, S. N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Preston, L., Newton, C. R. J. C., Edwards, Geoffrey and Kokwaro, G. O. (2005) 'Determination of midazolam and its major metabolite 1 '-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 821, Issue 1, pp. 1-7.

Mwai, L., Kokwaro, G., Borrmann, S. and Nzila, Alexis (2005) 'In vitro activity of piperaquine on Kenyan Plasmodium falciparum [MIM-LM-187777]'. Acta Tropica, Vol 95, S362-S363.

Mzilahowa, T., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and McCall, Philip ORCID: https://orcid.org/0000-0002-0007-3985 (2005) 'Sporozoite rates in Anopheles spp., and P. falciparum inbreeding coefficient in the Lower Shire Valley, southern Malawi [MIM-TM-10205]'. Acta Tropica, Vol 95, S183-S184.

N

Nduati, E., Hunt, S., Kamau, E. M. and Nzila, Alexis (2005) '2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials'. Antimicrobial Agents and Chemotherapy, Vol 49, Issue 9, pp. 3652-3657.

Nkhoma, Standwell, Molyneux, Malcolm E and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Relative fitness of wild type and mutant pfcrt parasites: An inference from direct in vitro growth competition experiments [MIM-SN-32913]'. Acta Tropica, Vol 95, S143-S143.

Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kevin, Sims, P. F. G. and Hyde, J. E. (2005) 'Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy'. Trends in Parasitology, Vol 21, Issue 6, pp. 292-298.

Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Marsh, Kevin, Sims, P. F. G. and Hyde, J. E. (2005) 'Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium'. Trends in Parasitology, Vol 21, Issue 7, pp. 334-339.

Nzila, Alexis, Ochong, Edwin, Nduati, E., Gilbert, K., Winstanley, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Marsh, Kevin (2005) 'Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 99, Issue 5, pp. 341-346.

O

O'Neill, P. M., Rawe, S. L., Borstnik, K., Miller, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Bray, Patrick, Davies, Jill, Oh, C. H. and Posner, G. H. (2005) 'Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: Implications for the molecular mechanism of action of the artemisinins'. Chembiochem, Vol 6, Issue 11, pp. 2048-2054.

O'Neill, P. M., Rawe, S. L., Storr, R. C., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Posner, G. H. (2005) 'Lewis acid catalysed rearrangements of unsaturated bicyclic [2.2.n] endoperoxides in the presence of vinyl silanes; access to novel Fenozan BO-7 analogues'. Tetrahedron Letters, Vol 46, Issue 17, pp. 3029-3032.

Ochola, Lucy, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Chance, Michael (2005) 'Investigating the role of PfRab5 in endocytosis in Plasmodium falciparum [MIM-LO-174325]'. Acta Tropica, Vol 95, S143-S144.

P

Phiri, H., Molyneux, Malcolm E, Montgomery, Jacqui and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2005) 'Binding sites on Intercellular adhesion molecule-1 (ICAM-1) for Plasmodium falciparum clinical isolates [MIM-HP-127554]'. Acta Tropica, Vol 95, S145-S145.

Poot, J., Rogers, Matthew E., Bates, Paul and Vermeulen, A. (2005) 'Detailed analysis of an experimental challenge model for Leishmania infantum (JPC strain) in dogs'. Veterinary Parasitology, Vol 130, Issue 1-2, pp. 41-53.

T

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Makunde, W. H., McGarry, Helen F., Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Mand, S. and Hoerauf, A. (2005) 'Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-control led trial'. Lancet, Vol 365, Issue 9477, pp. 2116-2121.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Bandi, C. and Hoerauf, A. (2005) 'Wolbachia bacterial endosymbionts of filarial nematodes'. Advances in Parasitology, Vol 60, pp. 245-284.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Langley, R. Stuart, Johnston, Kelly, Egerton, Gillian, Howard, R., Wanji, S. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2005) 'Filarial Wolbachia endosymbiotic bacteria mediate macrophage tolerance to TLR and CD40 stimuli in a MyD88 dependent manner'. Immunology, Vol 116, Issue supp 1, p. 24.

X

Xiao, C. A., Bator-Kelly, C. M., Rieder, E., Chipman, P. R., Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Kuhn, R. J., Wimmer, E. and Rossmann, M. G. (2005) 'The crystal structure of coxsackievirus A21 and its interaction with ICAM-1'. Structure, Vol 13, Issue 7, pp. 1019-1033.