Items where Department is "Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group" and Year is 2008

A

Ariaratnam, C. A., Sheriff, M. H. R., Theakston, R.David G. and Warrell, D. A. (2008) 'Distinctive epidemiologic and clinical features of common krait (Bungarus caeruleus) bites in Sri Lanka'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 3, pp. 458-462.

Ariaratnam, C. A., Thuraisingam, V., Kularatne, S. A. M., Sheriff, M. H. R., Theakston, R.David G., de Silva, A. and Warrell, D. A. (2008) 'Frequent and potentially fatal envenoming by hump-nosed pit vipers (Hypnale hypnale and H. nepa) in Sri Lanka: lack of effective antivenom'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 102, Issue 11, pp. 1120-1126.

B

Bates, Paul (2008) 'Leishmania and sand flies: Parasite-vector co-evolution or opportunism?'. Infection Genetics and Evolution, Vol 8, Issue 4, S1-S2.

Bates, Paul (2008) 'Leishmania sand fly interaction: progress and challenges'. Current Opinion in Microbiology, Vol 11, Issue 4, pp. 340-344.

Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791, Asadollahi, K., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Gill, Geoff (2008) Laboratory risk factors for hospital mortality - Reply. , Oxford University Press. 101. p. 64.

Bell, David J., Nyirongo, Suzgo K., Mukaka, Mavuto, Zijlstra, Ed E., Plowe, Christopher V., Molyneux, Malcolm E, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, Peter A. (2008) 'Sulfadoxine-pyrimethamine–based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in malawi'. PLoS ONE, Vol 3, Issue 2, e1578.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Williams, D. P., Bonar-Law, R., Bray, Patrick, Owen, A., O'Neill, P. M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: Selective and potent inhibitors of the malaria parasite mitochondrial bc(1) complex'. Molecular Pharmacology, Vol 73, Issue 5, pp. 1347-1355.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Bray, Patrick, Owen, A., O'Neill, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: a new class of potent inhibitors selective against the mitochondrial bc1 complex of the malaria parasite Plasmodium falciparum.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S41-S41.

Bray, Patrick (2008) 'Transport of folates and antifolates in Plasmodium falciparum.'. International Journal for Parasitology, Vol 38, S24-S24.

Bridges, D. J., Chakravorty, S., Bunn, J., O'Donnell, J., Grau, G. E., de Laat, B., van Mourik, J. A. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2008) 'The role of von Willebrand factor in malaria pathogenesis.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S65-S65.

C

Chakravorty, S., Hughes, K. R. and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2008) 'Host response to cytoadherence in Plasmodium falciparum'. Biochemical Society Transactions, Vol 36, pp. 221-228.

D

Dembo, E. G., Mwapasa, V., Montgomery, Jacqui, Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Porter, K. A., Meshnick, S. R., Molyneux, Malcolm E and Rogerson, S. J. (2008) 'Impact of human immunodeficiency virus infection in pregnant women on variant-specific immunity to malaria'. Clinical and Vaccine Immunology, Vol 15, Issue 4, pp. 617-621.

Dzinjalamala, F. K., Laufer, M. K., Thesing, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Reed, J. L., Hughes, D. M., Forrest, G., Taylor, T. E. and Plowe, C. V. (2008) 'Reversed-Phase High-Performance Liquid Chromatographic Assays for Determining Chloroquine in Whole Blood Specimens'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 290.

E

Ellis, G. L., Amewu, R., Sabbani, S., Stocks, Paul A., Shone, Alison, Stanford, D., Gibbons, P., Davies, Jill, Vivas, L., Charnaud, S., Bongard, E., Hall, Charlotte, Rimmer, Karen, Lozanom, S., Jesus, M., Gargallo, D., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles'. Journal of Medicinal Chemistry, Vol 51, Issue 7, pp. 2170-2177.

Ellis, Gemma L., Amewu, R., Hall, Charlotte, Rimmer, Karen, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2008) 'An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 5, pp. 1720-1724.

F

Fidock, D. A., Eastman, R. T., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Meshnick, S. R. (2008) 'Recent highlights in antimalarial drug resistance and chemotherapy research'. Trends in Parasitology, Vol 24, Issue 12, pp. 537-544.

Fisher, Nicholas, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2008) 'Modelling, cloning and expression of the P.falciparum NADH dehydrogenase'. Biochimica Et Biophysica Acta-Bioenergetics, Vol 1777, S38-S38.

Fisher, Nicholas and Meunier, B. (2008) 'Molecular basis of resistance to cytochrome bc(1) inhibitors'. Fems Yeast Research, Vol 8, Issue 2, pp. 183-192.

Ford, Louise, Johnston, Kelly, Ambrose, P. A., Draper, M. P., Bhatia, B. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'A-Wol Drug Discovery - Screening of Novel Derivatives of Tetracycline with Improved Efficacy over Doxycycline in an in Vitro Wolbachia Cell-Line Assay'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6, p. 128.

Foster, J. M., Kumar, S., Ford, Louise, Johnston, Kelly, Ben, R., Graeff-Teixeira, C. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'Absence of Wolbachia endobacteria in the non-filariid nematodes Angiostrongylus cantonensis and A. costaricensis'. Parasites & Vectors, Vol 1, e31.

G

Graham, R. L. J., Graham, C., Theakston, R.David G., McMullan, G. and Shaw, C. (2008) 'Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography'. Toxicon, Vol 51, Issue 1, pp. 121-129.

H

Habib, A. G., Abubakar, S. B., Abubakar, I. S., Larnyang, S., Durfa, N., Nasidi, A., Yusuf, P. O., Garnvwa, J., Theakston, R.David G., Salako, L. and Warrell, D. A. (2008) 'Envenoming after carpet viper (Echis ocellatus) bite during pregnancy: timely use of effective antivenom improves maternal and foetal outcomes'. Tropical Medicine & International Health, Vol 13, Issue 9, pp. 1172-1175.

Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X and Smith, T. A. (2008) 'MalHaploFreq: A computer programme for estimating malaria haplotype frequencies from blood samples'. Malaria Journal, Vol 7, p. 130.

Hoerauf, A., Specht, S., Buttner, M., Pfarr, K., Mand, S., Fimmers, R., Marfo-Debrekyei, Y., Konadu, P., Debrah, A. Y., Bandi, C., Brattig, N., Albers, A., Larbi, J., Batsa, L., Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Adjei, O. and Buttner, D. W. (2008) 'Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study'. Medical Microbiology and Immunology, Vol 197, Issue 3, pp. 295-311.

J

Janneh, O., Hartkoorn, R. C., Jones, E., Owen, A., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Davey, R., Back, D. J. and Khoo, S. H. (2008) 'Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir'. British Journal of Pharmacology, Vol 155, Issue 6, pp. 875-883.

Jenkins, N., Wu, Yang, Chakravorty, S., Kai, O., Marsh, Kevin and Craig, Alister (2008) 'Plasmodium falciparum Icam-1-based cytoadherence-related signalling in endothelical cells'. Journal of Infection, Vol 56, Issue 4, p. 299.

Johnson, David, Owen, A., Plant, N., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Drug-regulated expression of Plasmodium falciparum P-glycoprotein hornologue 1: a putative role for nuclear receptors'. Antimicrobial Agents and Chemotherapy, Vol 52, Issue 4, pp. 1438-1445.

Johnson, David and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Mechanisms of Drug Induced Gene Expression in Plasmodium Falciparum'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 301.

Johnson, David J., Owen, A., Plant, N. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Drug-regulated gene expression of Plasmodium falciparum P-glycoprotein homologue 1: a role for nuclear receptors?' in MAM 2008.

Johnston, Kelly, Wu, B., Guimaraes, A., Ford, Louise, Ambrose, Pauline, Slatko, B. E. and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2008) 'Globomycin: A New Class of Drug with Efficacy against Wolbachia and Filarial Nematodes'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Sup., p. 128.

M

Maier, A. G., Rug, M., O'Neill, M. T., Brown, M., Chakravorty, S., Szestak, Tadge, Chesson, J., Wu, Yang, Hughes, K., Coppel, R. L., Newbold, C., Beeson, J. G., Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Crabb, B. S. and Cowman, A. F. (2008) 'Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes'. Cell, Vol 134, Issue 1, pp. 48-61.

Maier, A. G., Rug, M., Brown, M., O'Neill, M. T., Chakravorty, S., Szestak, Tadge, Chesson, J., Wu, Yang, Hughes, K., Coppel, R., Newbold, C., Beeson, J., Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Crabb, B. S. and Cowman, A. F. (2008) 'The role of proteins exported to the Plasmodium falciparum-infected erythrocyte.'. International Journal for Parasitology, Vol 38, S18-S18.

Mandala, W. L., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Molyneux, Malcolm E and MacLennan, C. A. (2008) 'Leucocytes and Cytokine Production in Pathogenesis of Severe Malaria in Malawian Children'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 100.

Meunier, B. and Fisher, Nicholas (2008) 'Remodelling bc(1) complex Q(0) site in yeast to study acquired resistance to inhibitors'. Biochimica Et Biophysica Acta-Bioenergetics, Vol 1777, Issue Supplement 1 - EBEC: 2008 Abstract Book Supplement, S105-S106.

Montgomery, Jacqui, Kamiza, S., Carret, C., Ivens, A., Hunt, N. H., Taylor, T. E., Molyneux, Malcolm E and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2008) 'Host gene expression in fatal paediatric malaria.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S45-S45.

Muchohi, S. N., Obiero, K., Newton, C. R. J. C., Ogutu, B. R., Edwards, Geoffrey and Kokwaro, G. O. (2008) 'Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions'. British Journal of Clinical Pharmacology, Vol 65, Issue 1, pp. 12-21.

Muchohi, S. N., Kokwaro, G. O., Ogutu, B. R., Edwards, Geoffrey, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Newton, C. R. J. C. (2008) 'Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions'. British Journal of Clinical Pharmacology, Vol 66, Issue 4, pp. 529-538.

N

Naughton, J. A., Hughes, Ruth, Bray, Patrick and Bell, A. (2008) 'Accumulation of the antimalarial microtubule inhibitors trifluralin and vinblastine by Plasmodium falciparum'. Biochemical Pharmacology, Vol 75, Issue 8, pp. 1580-1587.

O

Ochola, Lucy, Marsh, Kevin, Siddondo, Bethseba, Svestak, Tadge and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2008) 'An analysis of ICAM-1 in Plasmodium falciparum malaria.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S81-S81.

Ochong, Edwin, Bell, David J., Johnson, David, D'Alessandro, U., Mulenga, M., Muangnoicharoen, Sant, Van Geertruyden, J. P., Winstanley, P. A., Bray, Patrick, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Owen, A. (2008) 'Plasmodium falciparum Strains Harboring Dihydrofolate Reductase with the I164L Mutation Are Absent in Malawi and Zambia Even under Antifolate Drug Pressure'. Antimicrobial Agents and Chemotherapy, Vol 52, Issue 11, pp. 3883-3888.

Ochong, Edwin, Salcedo, Enrique, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Owen, A. (2008) 'Transcriptional Analysis of Putative Folate Transporter Genes in Plasmodium Falciparum'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 302.

P

Phiri, H. T., Montgomery, Jacqui, Molyneux, Malcolm E and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2008) 'Competitive endothelial adhesion between Plasmodium falciparum isolates under physiological flow conditions.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S75-S76.

Pongtavornpinyo, W., Yeung, S., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Dondorp, A. M., Day, N. P. J. and White, N. J. (2008) 'Spread of anti-malarial drug resistance: Mathematical model with implications for ACT drug policies'. Malaria Journal, Vol 7, p. 229.

Premji, Z., Umeh, R. E., Owusu-Agyei, S., Esamai, F., Ezedinachi, E., Oguche, S., Borrmann, S., Sowunmi, A., Duparc, S., Kirby, P. L., Pamba, A., Kellam, L., Guiguemde, R., Greenwood, B., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Winstanley, P. A. (2008) 'Chlorproguanil-Dapsone-Artesu Nate Vs. Artemether-Lumefantrine: A Randomised, Double-Blind Phase Iii Trial for the Treatment of Acute, Uncomplicated Plasmodium Falciparum Malaria in African Children and Adolescents'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 225.

Q

Quashie, N. B., Dorin-Semblat, D., Bray, Patrick, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Doerig, C., Ranford-Cartwright, L. C. and de Koning, H. P. (2008) 'A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites'. Biochemical Journal, Vol 411, Issue 2, pp. 287-295.

R

Ranasinghe, S., Rogers, Matthew E., Hamilton, J. G. C., Bates, Paul and Maingon, R. D. C. (2008) 'A real-time PCR assay to estimate Leishmania chagasi load in its natural sand fly vector Lutzomyia longipalpis'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 102, Issue 9, pp. 875-882.

Reithinger, R., Dujardin, J. C., Louzir, H., Pirmez, C., Alexander, Bruce and Brooker, S. (2008) 'Cutaneous leishmaniasis - Reply'. Lancet Infectious Diseases, Vol 8, Issue 8, pp. 458-459.

Rodrigues Antao, Tiago, Lopes, A., Lopes, R. J., Beja-Pereira, A. and Luikart, G. (2008) 'LOSITAN: A workbench to detect molecular adaptation based on a F-st-outlier method'. Bmc Bioinformatics, Vol 9, Issue 323.

Rogers, Matthew E., Hajmova, M., Joshi, M. B., Sadlova, J., Dwyer, D. M., Volf, P. and Bates, Paul (2008) 'Leishmania chitinase facilitates colonization of sand fly vectors and enhances transmission to mice'. Cellular Microbiology, Vol 10, Issue 6, pp. 1363-1372.

S

Sabbani, S., Stocks, Paul A., Ellis, G. L., Davies, Jill, Hedenstrom, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Piperidine dispiro-1,2,4-trioxane analogues'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 21, pp. 5804-5808.

Sant'Anna, Mauricio R.V., Jones, N. G., Hindley, J. A., Mendes-Sousa, A. F., Dillon, Rod, Cavalcante, R. R., Alexander, Bruce and Bates, Paul (2008) 'Blood meal identification and parasite detection in laboratory-fed and field-captured Lutzomyia longipalpis by PCR using FTA databasing paper'. Acta Tropica, Vol 107, Issue 3, pp. 230-237.

Sant'Anna, Mauricio R.V., Alexander, Bruce, Bates, Paul and Dillon, Rod (2008) 'Gene silencing in phlebotomine sand flies: Xanthine dehydrogenase knock down by dsRNA microinjections'. Insect Biochemistry and Molecular Biology, Vol 38, Issue 6, pp. 652-660.

Santoro, M. L., Sano-Martins, I. S., Fan, H. W., Cardoso, J. L. C., Theakston, R.David G. and Warrell, D. A. (2008) 'Haematological evaluation of patients bitten by the jararaca, Bothrops jararaca, in Brazil'. Toxicon, Vol 51, Issue 8, pp. 1440-1448.

Siriwardana, H. V. Y. D., Noyes, H. A., Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791, Wickremasinghe, A. R., Chance, Michael, Bates, Paul and Karunaweera, N. D. (2008) 'Clinical Features of Cutaneous Leishmaniasis in Sri Lanka and Molecular Identification of L. donovani as the Cause'. International Journal of Infectious Diseases, Vol 12, Issue Suppl., E387-E387.

Siriwardana, Y. D., Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791, Noyes, H. A., Chance, Michael, Bates, Paul and Karunaweera, N. (2008) 'Genetically Distinct L.Donovani Causing Cutanoues Leishmaniasis in Sri Lanka: A Study on Leishmania Species/Strain Variation'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 162.

Skidmore, M. A., Dumax-Vorzet, A. F., Guimond, S. E., Rudd, T. R., Edwards, E. A., Turnbull, J. E., Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 and Yates, E. A. (2008) 'Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities'. Journal of Medicinal Chemistry, Vol 51, Issue 5, pp. 1453-1458.

Straimer, J., Sasi, P., Abdulrahaman, A., Rippert, A., Mwai, L., Schieck, E., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Borrmann, S. (2008) 'Relationship between Persistence of Subpatent Asexual Plasmodium Falciparum Infections and Subsequent Recrudescence after Antimalarial Treatment'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 291.

T

Tiono, A., Dicko, A., Nclububa, D. A., Abenyega, T., Pitmang, S., Awobusuyi, J., Pamba, A., Duparc, S., Goh, L. E., Harrell, E., Carter, N., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Greenwood, B. and Winstanley, P. A. (2008) 'Chlorproguanil-Dapsone-Artesunate Vs. Chlorproguanil-Dapsone: A Randomised, Double-Blind Phase Iii Trial for the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria'. American Journal of Tropical Medicine and Hygiene, Vol 79, Issue 6 Supp, p. 172.

V

Verissimo, E., Berry, N., Gibbons, P., Cristiano, M. L. S., Rosenthal, P. J., Gut, J., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2008) 'Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors'. Bioorganic & Medicinal Chemistry Letters, Vol 18, Issue 14, pp. 4210-4214.

W

Wu, Yang, Preston, G. and Bianco, Albert E. (2008) 'Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi'. Molecular and Biochemical Parasitology, Vol 161, Issue 1, pp. 55-62.