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Folic Acid Supplementation in Chinese Peri-conceptional Population: Results from the SPCC Study

WANG, Ding Mei, ZHANG, Yi, YE, Ying, HUANG, Xiang Yuan, LI, Meng Ru, JI, Mi, ZHAO, Zheng Shan, CHEN, Xiao Ying, SHENG, Wei, MA, Xiao Jing, Allen, Stephen ORCID: https://orcid.org/0000-0001-6675-249X, Wang, Duolao ORCID: https://orcid.org/0000-0003-2788-2464, YAN, Wei Li and HUANG, Guo Ying (2020) 'Folic Acid Supplementation in Chinese Peri-conceptional Population: Results from the SPCC Study'. Biomedical and Environmental Sciences, Vol 33, Issue 8, pp. 557-565.

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Abstract

Objective To determine the prevalence and determinants of folic acid (FA) supplementation in Chinese couples planning for pregnancy and in women during early pregnancy.
Methods This was a cross-sectional study based on the Shanghai PreConception Cohort (SPCC) study. Data on FA supplementation and socio-demographic features were collected using questionnaires. Couples visiting clinics for pre-pregnancy examination and pregnant women at < 14 gestational weeks were recruited in Shanghai, China, between March 2016 and September 2018.
Results Among the pregnancy planners, 42.4% (4710/11,099) women and 17.1% (1377/8045) men used FA supplements, while 93.4% (14,585/15,615) of the pregnant women used FA supplements. FA supplement use was higher in female pregnancy planners who were older (RR:1.13, 95%CI:1.08–1.18), had higher education (RR:1.71, 95%CI:1.53–1.92), and were residing in urban districts (RR:1.06, 95%CI:1.01–1.11) of FA supplementation; female pregnancy planners with alcohol consumption (RR:0.95, 95%CI:0.90–0.99) had lower odds of FA supplementation. In early pregnancy, women with higher educational level (RR:1.04, 95%CI:1.03–1.06), who underwent pre-pregnancy examination (RR:1.02, 95%CI:1.01–1.03) had higher odds of using an FA supplement; older aged (RR:0.99, 95% CI:0.98–0.99), and multigravida (RR:0.97, 95% CI:0.96–0.98) had lower odds of FA supplementation

Item Type: Article
Subjects: QU Biochemistry > Vitamins > QU 188 Folic acid
WA Public Health > Health Problems of Special Population Groups > WA 309 Women's health
WA Public Health > Health Problems of Special Population Groups > WA 310 Maternal welfare
WQ Obstetrics > Childbirth. Prenatal Care > WQ 175 Prenatal care
WQ Obstetrics > Pregnancy > WQ 200 General works
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.3967/bes2020.074
Depositing User: Claire McIntyre
Date Deposited: 17 Sep 2020 09:14
Last Modified: 17 Sep 2020 09:15
URI: https://archive.lstmed.ac.uk/id/eprint/14770

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