Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): implications for snail systematics and schistosome epidemiology

Young, Neil David, Kinkar, Liina, Stroehlein, Liina, Korhonen, Pasi K., Stothard, j. Russell ORCID: https://orcid.org/0000-0002-9370-3420, Rollinson, David and Gasser, Robin B. (2021) 'Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): implications for snail systematics and schistosome epidemiology'. Current Research in Parasitology and Vector-Borne Diseases, Vol 2021, Issue 1, p. 100017.

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Abstract

Many freshwater snails of the genus Bulinus act as intermediate hosts in the life cycles of schistosomes in Africa and adjacent regions. Currently, 37 species of Bulinus representing four groups are recognised. The mitochondrial cytochrome c oxidase subunit 1 (cox1) gene has shown utility for identifying and differentiating Bulinus species and groups, but taxonomic relationships based on genetic data are not entirely consistent with those inferred using morphological and biological features. To underpin future systematic studies of members of the genus, we characterised here the mitochondrial genome of Bulinus truncatus (from a defined laboratory strain) using a combined second- and third-generation sequencing and informatics approach, enabling taxonomic comparisons with other planorbid snails for which mt genomes were available. Analyses showed consistency in gene order and length among mitochondrial genomes of representative planorbid snails, with the lowest and highest nucleotide diversities being in the cytochrome c oxidase and nicotinamide dehydrogenase subunit genes, respectively. This first mt genome for a representative of the genus Bulinus should provide a useful resource for future investigations of the systematics, population genetics, epidemiology and/or ecology of Bulinus and related snails. The sequencing and informatic workflow employed here should find broad applicability to a range of other snail vectors of parasitic trematodes.

Item Type:	Article
Subjects:	QU Biochemistry > QU 26.5 Informatics. Automatic data processing. Computers QU Biochemistry > Proteins. Amino Acids. Peptides > QU 58.5 DNA. QX Parasitology > Helminths. Annelida > QX 355 Schistosoma QX Parasitology > Insects. Other Parasites > QX 675 Mollusca WC Communicable Diseases > Tropical and Parasitic Diseases > WC 810 Schistosomiasis
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.crpvbd.2021.100017
Depositing User:	Cathy Waldron
Date Deposited:	25 Feb 2021 10:51
Last Modified:	06 Apr 2021 14:57
URI:	https://archive.lstmed.ac.uk/id/eprint/16970

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