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Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project

Deloria Knoll, Maria, Bennett, Julia, Garcia Quesada, Maria, Kagucia, Eunice, Peterson, Meagan, Feikin, Daniel, Cohen, Adam, Hetrich, Marissa, Yang, Yangyupei, Sinkevitch, Jenna, Ampofo, Krow, Aukes, Laurie, Bacci, Sabrina, Bigogo, Godfrey, Brandileone, Maria-Cristina, Bruce, Michael, Camilli, Romina, Castilla, Jesús, Chan, Guanhao, Chanto Chacón, Grettel, Ciruela, Pilar, Cook, Heather, Corcoran, Mary, Dagan, Ron, Danis, Kostas, de Miguel, Sara, De Wals, Philippe, Desmet, Stefanie, Galloway, Yvonne, Georgakopoulou, Theano, Hammitt, Laura, Hilty, Markus, Ho, Pak-Leung, Jayasinghe, Sanjay, Kellner, James, Kleynhans, Jackie, Knol, Mirjam, Kozakova, Jana, Kristinsson, Karl, Ladhani, Shamez, Lara, Claudia, León, Maria, Lepp, Tiia, Mackenzie, Grant, Mad’arová, Lucia, McGeer, Allison, Mungun, Tuya, Mwenda, Jason, Nuorti, J., Nzoyikorera, Néhémie, Oishi, Kazunori, De Oliveira, Lucia, Paragi, Metka, Pilishvili, Tamara, Puentes, Rodrigo, Rafai, Eric, Saha, Samir, Savrasova, Larisa, Savulescu, Camelia, Scott, J., Scott, Kevin, Serhan, Fatima, Setchanova, Lena, Sinkovec Zorko, Nadja, Skoczyńska, Anna, Swarthout, Todd, Valentiner-Branth, Palle, van der Linden, Mark, Vestrheim, Didrik, von Gottberg, Anne, Yildirim, Inci and Hayford, Kyla (2021) 'Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project'. Microorganisms, Vol 9, Issue 4, p. 742.

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Serotype-specific surveillance for invasive pneumococcal disease (IPD) is essential for assessing the impact of 10- and 13-valent pneumococcal conjugate vaccines (PCV10/13). The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project aimed to evaluate the global evidence to estimate the impact of PCV10/13 by age, product, schedule, and syndrome. Here we systematically characterize and summarize the global landscape of routine serotype-specific IPD surveillance in PCV10/13-using countries and describe the subset that are included in PSERENADE. Of 138 countries using PCV10/13 as of 2018, we identified 109 with IPD surveillance systems, 76 of which met PSERENADE data collection eligibility criteria. PSERENADE received data from most (n = 63, 82.9%), yielding 240,639 post-PCV10/13 introduction IPD cases. Pediatric and adult surveillance was represented from all geographic regions but was limited from lower income and high-burden countries. In PSERENADE, 18 sites evaluated PCV10, 42 PCV13, and 17 both; 17 sites used a 3 + 0 schedule, 38 used 2 + 1, 13 used 3 + 1, and 9 used mixed schedules. With such a sizeable and generally representative dataset, PSERENADE will be able to conduct robust analyses to estimate PCV impact and inform policy at national and global levels regarding adult immunization, schedule, and product choice, including for higher valency PCVs on the horizon

Item Type: Article
Subjects: QW Microbiology and Immunology > Antigens and Antibodies. Toxins and Antitoxins > QW 570 Serology.
WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 217 Pneumococcal infections
Faculty: Department: Clinical Sciences & International Health > Malawi-Liverpool-Wellcome Programme (MLW)
Digital Object Identifer (DOI):
Depositing User: Stacy Murtagh
Date Deposited: 10 May 2021 13:36
Last Modified: 10 May 2021 13:36


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