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Brouwer, Michael S.M., de Freitas Costa, Eduardo, Dame-Korevaar, Anita, Roberts, Adam 
ORCID: https://orcid.org/0000-0002-0760-3088 and Veldman, Kees T.
(2024)
'Extended spectrum cephalosporin (ESC) resistant Escherichia coli: trends and seasonality in the Netherlands from 2014–2022'. One Health, Vol 3, p. 100083.
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Abstract
Background
Antimicrobial resistance (AMR) in livestock and the environment likely contribute to the prevalence of AMR in humans with potential detrimental effects on human health. As such, annual mandatory monitoring of AMR in livestock occurs within the European Union (EU), according to harmonised methods. Extended-spectrum cephalosporins-resistant (ESC-resistant) Escherichia coli, including extended-spectrum β-lactamases (ESBL), AmpC β-lactamases (AmpC) and carbapenemase producing E. coli, are considered of particular importance and are therefore included in the monitoring program.
Methods
Using results from the annual monitoring of ESC-resistant E. coli from 2014–2022, trends in prevalence per animal sector were determined over the complete time period, as well as potential seasonal effects.
Results
During these nine years, significant changes were observed in the prevalence of ESC-resistant E. coli, in broilers, dairy cattle and veal calves, while no changes in prevalence were seen in slaughter pigs. Furthermore, the prevalence of ESC-resistant E. coli is positively correlated with warmer seasons (summer and autumn) for both dairy cattle and veal calves, while no associations were found for broilers and slaughter pigs. While temperature itself may play a role in the prevalence of ESC-resistant E. coli, other factors affecting the selective landscape, such as antibiotic usage, will also play a role.
Conclusion
A combined analysis of antimicrobial usage and prevalence of ESC-resistant E. coli through the year, both in livestock and human samples, would be an interesting follow-up of this study.
| Item Type: | Article |
|---|---|
| Subjects: | QV Pharmacology > Anti-Bacterial Agents. Tissue Extracts > QV 350.5.C3 Cephalosporins QW Microbiology and Immunology > QW 45 Microbial drug resistance. General or not elsewhere classified. WC Communicable Diseases > Infection. Bacterial Infections > Enteric Infections > WC 290 Escherichia coli infections |
| Faculty: Department: | Biological Sciences > Department of Tropical Disease Biology |
| Digital Object Identifer (DOI): | https://doi.org/10.1016/j.soh.2024.100083 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 14 Nov 2024 12:29 |
| Last Modified: | 14 Nov 2024 12:29 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/25545 |
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