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Carotid intima-media thickness is a predictor of coronary artery disease in South African black patients

Holland, Z., Ntyintyane, L. M., Gill, Geoff and Raal, F. J. (2009) 'Carotid intima-media thickness is a predictor of coronary artery disease in South African black patients'. Cardiovascular Journal of Africa, Vol 20, Issue 4, pp. 237-239.

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Background: Several studies have shown that increased carotid intima-media thickness (CIMT) confers risk of future coronary artery disease (CAD) and stroke. The present study aimed at investigating whether CIMT is a predictor of CAD in South African black patients. Methods and Results: This was a prospective study of 53 patients, 41 men and 12 women, with ages ranging from 30 to 70 years. All patients had undergone coronary angiography for suspected CAD. B-mode ultrasound measurement of the carotid intima-media thickness was carried out in all patients, the operator being blinded to the coronary angiography findings. Twenty-nine of the 38 (76%) subjects with established CAD had increased CIMT, with an average mean CIMT of 1.13 mm. Single-vessel disease was present in 12 people, double-vessel disease in 11 and triple-vessel disease in 12. There was a significant positive linear trend between CIMT and the number of involved coronary vessels (p < 0.0001, r = 0.44). Conclusions: Increased CIMT correlated with evidence of angiographically proven CAD. The median percentile scores showed a progressive increase as the number of vessels involved increased. CIMT could be useful as a screening tool for the presence of CAD in the South African black population.

Item Type: Article
Uncontrolled Keywords: adult aged angiocardiography arterial wall thickness article B scan cardiovascular risk carotid artery clinical article controlled study coronary artery disease correlation analysis female human male Negro prediction prospective study screening test South Africa stroke African Continental Ancestry Group Carotid Arteries Humans Middle Aged Predictive Value of Tests Prospective Studies Tunica Intima Tunica Media
Subjects: WG Cardiovascular System > WG 20 Research (General)
WG Cardiovascular System > WG 120 Cardiovascular diseases
WG Cardiovascular System > Heart. Heart Diseases > WG 200 General works
Faculty: Department: Groups (2002 - 2012) > Clinical Group
Depositing User: Users 43 not found.
Date Deposited: 23 Jun 2010 11:14
Last Modified: 06 Feb 2018 12:59


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