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Carotid intima-media thickness is a predictor of coronary artery disease in South African black patients

Holland, Z., Ntyintyane, L. M., Gill, Geoff and Raal, F. J. (2009) 'Carotid intima-media thickness is a predictor of coronary artery disease in South African black patients'. Cardiovascular Journal of Africa, Vol 20, Issue 4, pp. 237-239.

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Abstract

Background: Several studies have shown that increased carotid intima-media thickness (CIMT) confers risk of future coronary artery disease (CAD) and stroke. The present study aimed at investigating whether CIMT is a predictor of CAD in South African black patients. Methods and Results: This was a prospective study of 53 patients, 41 men and 12 women, with ages ranging from 30 to 70 years. All patients had undergone coronary angiography for suspected CAD. B-mode ultrasound measurement of the carotid intima-media thickness was carried out in all patients, the operator being blinded to the coronary angiography findings. Twenty-nine of the 38 (76%) subjects with established CAD had increased CIMT, with an average mean CIMT of 1.13 mm. Single-vessel disease was present in 12 people, double-vessel disease in 11 and triple-vessel disease in 12. There was a significant positive linear trend between CIMT and the number of involved coronary vessels (p < 0.0001, r = 0.44). Conclusions: Increased CIMT correlated with evidence of angiographically proven CAD. The median percentile scores showed a progressive increase as the number of vessels involved increased. CIMT could be useful as a screening tool for the presence of CAD in the South African black population.

Item Type: Article
Subjects: WG Cardiovascular System > WG 20 Research (General)
WG Cardiovascular System > WG 120 Cardiovascular diseases
WG Cardiovascular System > Heart. Heart Diseases > WG 200 General works
Depositing User: Users 43 not found.
Date Deposited: 23 Jun 2010 11:14
Last Modified: 20 Nov 2024 12:51
URI: https://archive.lstmed.ac.uk/id/eprint/285

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