Recognition of risk for clinically significant drug interactions among HIV-infected patients receiving antiretroviral therapy.

Evans-Jones, J., Cottle, L., Back, D.J., Gibbons, S., Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791, Carey, P. and Khoo, S.H. (2010) 'Recognition of risk for clinically significant drug interactions among HIV-infected patients receiving antiretroviral therapy.'. Clinical Infectious Diseases, Vol 50, Issue 10, pp. 1419-1421.

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Abstract

We assessed the risk of clinically significant drug interactions in patients receiving antiretrovirals, and their recognition by physicians. Clinically significant drug interactions were recorded in 27% of 159 patients, with 15% of interactions potentially lowering antiretroviral concentrations. Risk of clinically significant drug interactions was significantly related to receipt of protease inhibitors. Only 36% of clinically significant drug interactions were correctly identified by physicians.

Item Type:	Article
Additional Information:	Originally published at: http://www.journals.uchicago.edu/doi/abs/10.1086/652149
Subjects:	QV Pharmacology > Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > QV 268.5 Antiviral agents (General) WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.2 Therapy
Digital Object Identifer (DOI):	https://doi.org/10.1086/652149
Depositing User:	Users 43 not found.
Date Deposited:	15 Jul 2010 11:36
Last Modified:	09 Sep 2019 06:25
URI:	https://archive.lstmed.ac.uk/id/eprint/1030

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